2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ikemikari yemakemikari inowanzoshandiswa mumakemikari emakemikari uye glycosylation reactions.Inobva ku-α-D-galactopyranose, rudzi rweshuga, uko mapoka ehydroxyl ari pa2, 3, 4, uye 6 nzvimbo dzemhete yegalactopyranose ane acetylated.Uyezve, iyo anomeric carbon (C1) yeshuga inodzivirirwa neboka re trichloroacetimidate, iyo inoita kuti ive electrophile yakasimba panguva ye glycosylation reactions.

Iyo kompani inowanzoshandiswa se glycosylating agent kuunza galactose moieties mumamorekuru akasiyana, senge mapuroteni, peptides, kana madiki organic mamorekuru.Izvi zvinogona kuwanikwa kuburikidza nekuita iyi komisheni ine nucleophile (semuenzaniso, hydroxyl mapoka pane inonangwa molecule) pasi pemamiriro akakodzera.Iro trichloroacetimidate boka rinofambisa kubatanidzwa kwegalactose moiety kune chinangwa che molecule, zvichiita kuti pave nekugadzirwa kweglycosidic bond.

Mushonga uyu unowanzoshandiswa mukugadzira glycoconjugates, glycopeptides, uye glycolipids.Inopa nzira inochinja-chinja uye inoshanda yekushandura mamorekuru ane galactose masara, ayo anogona kuve akakodzera munzvimbo dzakasiyana siyana, kusanganisira zvidzidzo zvebhayoloji, masisitimu ekutumira zvinodhaka, kana kuvandudza vaccine.

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Application uye Effect

Glycosylation: Mushonga unopindirana neakasiyana-siyana anogamuchira mamorekuru ane hydroxyl mapoka, akadai sedoro kana maamines, kugadzira glycosidic bond.Izvi zvinobvumira kuiswa kwegalactose pane anogamuchira molecule, zvichiita kuti pave nekugadzirwa kwe glycojugates, glycopeptides, kana glycolipids.

Zvidzidzo zvebiochemical uye biological: Mushonga unobatsira vaongorori kudzidza mabasa ebhayoloji uye kudyidzana kwemamorekuru ane galactose.Nekusarudza kuisa galactose kumapuroteni, peptides, kana mamwe mabiomolecules, vaongorori vanogona kuongorora mabasa avo mumaserura maitiro, kupindirana kwe-receptor-ligand, uye nzira dzechirwere.

Mishonga yekuendesa zvinodhaka: Iyo kompani inogona kushandiswa kushandura mamorekuru emishonga ane galactose masara, kufambisa yakanangwa yekuendesa zvinodhaka kune chaiwo tishu kana masero.Galactose inogona kuita senge rakananga ligand, ichiziva zvakagamuchirwa zvinogamuchirwa pamusoro pemasero, kunyanya hepatocytes.Nekubatanidza galactose kumishonga, vatsvakurudzi vanogona kuwedzera kusarudza kwavo uye kushanda mukurapa kwakanangwa.

Kuvandudzwa kwejekiseni: Mamorekuru ane galactose anoita basa rakakosha mumhinduro dzekudzivirira zvirwere, sezvo achizivikanwa nemalectins aripo pamasero edziviriro.Nekubatanidza maantigen ane galactose moieties vachishandisa musanganiswa uyu, vaongorori vanogona kusimudzira mhinduro dzekudzivirira zvirwere uye kugadzira majekiseni anoshanda.

Kemikari synthesis: Mushonga wacho unogona kushandiswa mune akasiyana makemikari syntheses uko galactose shanduko inodiwa.Izvi zvinosanganisira kugadzirwa kwezvakaoma carbohydrate zvimiro, oligosaccharides, kana glycomimetics, iyo inogona kushandiswa zvakare mumakemikari emishonga kana sematurusi ekutsvaga.

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Ruzivo Rwokuwedzera:

Composition	C16H20Cl3NO10
Assay	99%
Chitarisiko	Upfu chena
CAS Nha.	86520-63-0
Packing	Zvidiki uye zvakawanda
Sherufu Hupenyu	2 years
Storage	Chengetedza munzvimbo inotonhorera uye yakaoma
Certification	ISO.