2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ikemikari inoshandiswa zvakanyanya mumakemikari emacarbohydrate uye glycosylation reactions. Inobva kuα-D-galactopyranose, rudzi rweshuga, uko mapoka ehydroxyl ari panzvimbo dze2, 3, 4, uye 6 dzegalactopyranose ring akagadzirwa neacetylated. Pamusoro pezvo, anomeric carbon (C1) yeshuga inodzivirirwa neboka retrichloroacetimidate, izvo zvinoita kuti ive electrophile yakasimba panguva yeglycosylation reactions.

Musanganiswa uyu unowanzo shandiswa semushonga weglycosylating kuisa galactose moieties mumamorekuru akasiyana-siyana, akadai semapuroteni, mapeptide, kana mamorekuru madiki eorganic. Izvi zvinogona kuitwa nekuita kuti musanganiswa uyu ushande ne nucleophile (semuenzaniso, mapoka ehydroxyl pamorekuru yaunoda) mumamiriro ezvinhu akakodzera. Boka re trichloroacetimidate rinobatsira kuti galactose moiety ibatanidzwe kune molecule yaunoda, zvichikonzera kuumbwa kweglycosidic bond.

Mushonga uyu unoshandiswa zvakanyanya mukugadzirwa kwemaglycoconjugates, glycopeptides, uye glycolipids. Unopa nzira inoshanda uye inoshanda yekugadzirisa mamorekuru ane galactose residues, ayo anogona kushanda munzvimbo dzakasiyana siyana, kusanganisira zvidzidzo zvebhayoloji, masisitimu ekupa mishonga, kana kugadzira majekiseni.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Glycosylation: Musanganiswa uyu unoshanda nemamorekuru akasiyana-siyana ekugamuchira ane mapoka ehydroxyl, akadai sealcohols kana amines, kuti ugadzire ma glycosidic bonds. Izvi zvinobvumira kuiswa kwegalactose pamorekuru yekugamuchira, zvichikonzera kugadzirwa kweglycoconjugates, glycopeptides, kana glycolipids.

Zvidzidzo zve biochemical uye zve biological: Musanganiswa uyu unobatsira vaongorori kudzidza mashandiro e biological uye kudyidzana kwemamorekuru ane galactose. Nekubatanidza galactose nemapuroteni, mapeptide, kana mamwe ma biomolecule, vaongorori vanogona kuongorora mabasa avo mumasero, kudyidzana kwema receptor-ligand, uye mashandiro ezvirwere.

Masisitimu ekupa mishonga: Mushonga uyu unogona kushandiswa kugadzirisa mamorekuru emishonga ane galactose residues, zvichiita kuti mushonga upinzwe kune mamwe matishu kana masero. Galactose inogona kushanda senzira yekutarisa, ichiziva mareceptor chaiwo anoratidzwa pamusoro pemasero, kunyanya hepatocytes. Nekubatanidza galactose nemishonga, vaongorori vanogona kuwedzera kusarudza kwavo uye kushanda kwavo mukurapa kwakanangwa.

Kugadzirwa kwejekiseni: Mamorekuru ane Galactose anoita basa rakakosha mukupindura kwemuviri kuzvirwere, sezvo achizivikanwa nema lectin ari pamasero emuviri. Nekubatanidza maantigen nezvikamu zve galactose vachishandisa chinhu ichi, vaongorori vanogona kuwedzera mhinduro dzemuviri kuzvirwere uye kugadzira majekiseni anoshanda zvakanyanya.

Kugadzirwa kwemakemikari: Musanganiswa uyu unogona kushandiswa mukugadzirwa kwemakemikari akasiyana-siyana uko kunodiwa kugadzirisa galactose. Izvi zvinosanganisira kugadzirwa kwema complex carbohydrate structures, oligosaccharides, kana glycomimetics, izvo zvinogona kushandiswa zvakare mumishonga kana sezvishandiso zvekutsvagisa.

Muenzaniso weChigadzirwa

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C16H20Cl3NO10
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	86520-63-0
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.