Gabapentin CAS:60142-96-3 Mugadziri Wekutengesa

Gabapentin is amino acid yakarongeka ine hukama ne γ-Aminobutyric Acid (GABA), yakagadzirirwa kuyambuka uropi hweropa.Inoshandiswa se anticonvulsant.Inotemerwawo kune multiple sclerosis varwere kudzora dysesthesias uye inogona kubatsira mukuderedza marwadzo neuropathic anokonzerwa nekenza uye hutachiona hweHIV.Iyo haisungiri kuGABA receptors, haina kukanganisa neural uptake yeGABA, uye haidziviriri GABA-metabolizing enzyme, GABA transaminase.Kusiyana neGABA, iyo isingapfuuri neropa-brain barriers, gabapentin inopinda mukati mehutano hwemagetsi uye inosunga kune α2δ-type voltage-gated calcium channels.Iyo nzira yeanalgesic uye anticonvulsant mhedzisiro ye gabapentin haizivikanwe.