Candesartana Cilexetila CAS:145040-37-5

Candesartan Celexetil imhando ye ester analog ye angiotensin II antagonist Candesartan (sc-217825). Kusawirirana kwemushonga uyu kunodzivirira kusunga kwe angiotensin II, vasoconstrictor ine simba. Izvi zvine mhedzisiro yese yekuwedzera kweropa uye kuwedzera kwehuwandu hweropa mu capillary. Candesartan Celexetil Ester inodzivirira AT1.

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Kushandiswa uye Mhedzisiro

Candesartan cilexetil mushonga unobva ku candesartan, mushonga une simba, unoshanda kwenguva refu, uye unosarudza angiotensin II type 1 receptor antagonist, unonzi candesartan. Unokurumidza kunyungudutswa kuita candesartan panguva yekunyungudutswa kwemudumbu. Mushure mekunyungudutswa kwe candesartan cilexetil kuenda ku candesartan panguva yekunyungudutswa kwemudumbu, candesartan inokwikwidzana ne angiotensin II kuti isunge angiotensin II receptor subtype 1 AT1 mutsandanyama dzakatsetseka dzeropa, ichivhara angiotensin II-mediated vasoconstriction uye ichikonzera vasodilatation. Pamusoro pezvo, kupikiswa kweAT1 muadrenal gland kunodzivisa kugadzirwa kwealdosterone inosimudzirwa neadrenal cortex neangiotensin II; kuwedzera kwe sodium nemvura, zvichiteverwa nekudzikira kwehuwandu hweplasma uye BP.

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Mamwe Mashoko:

Kuumbwa	C33H34N6O6
Kuyedza	99%
Chitarisiko	Upfu Huchena
Nhamba yeCAS	145040-37-5
Kurongedza	1KG 25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.