Linagliptin CAS:668270-12-0 Mugadziri weMugadziri Mufananidzo Wakaratidzwa

Linagliptin CAS:668270-12-0 Mugadziri wezvigadzirwa

Linagliptin (mazita ekutengeserana eTradjenta naTrajetna) inodzivirira dipeptidyl peptidase-4 (DPP-4) yakatenderwa neUS FDA muna Chivabvu 2011 kurapa chirwere cheshuga cheType 2 pamwe nekudya uye kurovedza muviri. Linagliptin (BI-1356) yakatsanangurwa semushonga unosarudza zvakanyanya, unononoka uye unodzivirira kwenguva refu weDPP-4. Linagliptin yakabva mukuedza kwekuvandudza kwemishonga inodzivirira DPP-4 inobva kuxanthine ne lead yekutanga yakawanikwa kubva kuchirongwa cheHTS.

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Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) mushonga unodzivisa dipeptidyl peptidase-4 nemuromo uye ndiwo mushonga wekutanga weboka rayo kubviswa zvakanyanya kuburikidza nenzira isiri yeitsvo. Linagliptin inoratidzwa kushandiswa kamwe chete pazuva kurapa vanhu vakuru vane chirwere cheshuga cherudzi rwechipiri. Linagliptin inoshanda kuderedza huwandu hweshuga muropa nekudzivisa enzyme DPP-4, nokudaro ichidzivirira kuparara kwemahormone eincretin (glucagon-like peptide-1 [GLP-1] uye glucose-dependent insulinotropic peptide) uye kuderedza kubuda kweshuga mushure mekudya.

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Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C25H28N8O2
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	668270-12-0
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.