Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Mugadziri Mugadziri

Sodium Alpha-Ketoisocaproate inonzi leucine metabolite inozivikanwa kuti iite insulin secretion kubva kuma βcells epancreas.Enteral infusion yeaa-Ketoisocaproate inowanikwa kuti iwedzere, endotoxemic mamiriro.Mitumbi yeketone inoguma yakawanikwa kubva mukushandurwa kwayo, inogona kushanda sesimba rekushandisa.Kuunganidza kwe-α-Ketoisocaproic acid inoratidzirwa muketani yeketani ketoaciduria, iyo inokonzerwa nekushayikwa kweketani yeketani L-2-keto acid dehydrogenase basa.α-Ketoisocaproic acid inokonzera kuparadzaniswa mu oxidative phosphorylation reaction uye inoshanda se metabolic inhibitor ye α-ketoglutarate dehydrogenase.Nokudaro, zvinotungamirira kune chikanganiso mumitochondrial homeostasis, inoonekwa mu branched chain ketoaciduria.