Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Mugadziri weMugadziri

Sodium Alpha-Ketoisocaproate imhando ye leucine metabolite inozivikanwa nekuburitsa insulin kubva kumasero epancreatic. Kuiswa kwe aα-Ketoisocaproate mukati medumbu kunowanikwa kuchivandudza mamiriro e endotox. Miviri ye ketone inowanikwa kubva mukushandurwa kwayo, inogona kushanda senzvimbo yesimba. Kuunganidzwa kwe α-Ketoisocaproic acid kunoratidzwa mu branched chain ketoaciduria, iyo inokonzerwa nekushaikwa kwe branched chain L-2-keto acid dehydrogenase activity. α-Ketoisocaproic acid inokonzera kupatsanurwa mu oxidative phosphorylation reaction uye inoshanda se metabolic inhibitor ye α-ketoglutarate dehydrogenase. Saka, zvinotungamira kune defect mu mitochondrial homeostasis, inoonekwa mu branched chain ketoaciduria.