2′-(4-METHYLUMBELLIFERIFERIL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM MUNYU CAS:76204-02-9

2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium salt ikemikari inoshandiswa zvakanyanya mukuongorora nekuongorora. Inobva ku sialic acid ine fluorescent, rudzi rwe carbohydrate molecule inowanikwa pamusoro pemasero.

Mushonga uyu unoshandiswa sechikamu chema enzymes anonzi neuraminidases, ayo anoshanda kubvisa ma residues ealic acid kubva kuma glycoproteins nema glycolipids. Kana ma enzymes aya achishanda pa 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium salt, inoburitsa chigadzirwa che fluorescent chinozivikanwa se 4-methylumbelliferone.

Kupenya kunokonzerwa nechinhu ichi kunogona kuyerwa nekuverengwa, zvichipa ruzivo nezvebasa rema enzymes e neuraminidase. Izvi zvinobatsira zvikuru mukudzidza zvirwere zvakasiyana-siyana nemamiriro ezvinhu ane chekuita ne metabolism ye sialic acid isina kujairika.

Mushonga uyu unoshandiswawo pakuongorora zvirwere, zvakaita sekuona hutachiona hunosanganisira neuraminidase activity. Mukuongorora uku, mushonga uyu unoshandiswa kuona kuvapo kwemarudzi chaiwo ehutachiona kana kuongorora kushanda kwemishonga inodzivirira neuraminidase mukurapa mavhairasi.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Kuyedzwa kweNeuraminidase Activity: Mushonga uyu unowanzoshandiswa kuyera mashandiro emaenzymes eNeuraminidase mumienzaniso yehupenyu. Nekutarisa fluorescence inogadzirwa, vaongorori vanogona kuona huwandu hwemabasa eNeuraminidase, izvo zvinogona kubatsira mukudzidza zvirwere zvakasiyana-siyana nemamiriro ezvinhu.

Kuonekwa kwehutachiona hwemavhairasi: Mavhairasi mazhinji, kusanganisira furuwenza, ane chekuita ne neuraminidase activity. Mushonga uyu unogona kushandiswa kuona nekuyera kuvapo kwemarudzi chaiwo ehutachiona nekuyera mashandiro e fluorescent. Unonyanya kubatsira pakuongorora kushanda kwe neuraminidase inhibitors mukurapa mavhairasi.

Kuongorora Glycosylation: Sialic acid chinhu chakakosha mumaglycoprotein nemaglycolipids. Nekubatanidza 2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium salt mukuyedza, vaongorori vanogona kuwana ruzivo nezve metabolism yesialic acid, mapatani eglycosylation, uye maitiro ane chekuita nemuviri.

Kuwanikwa Kwemishonga: Mishonga inodzivirira neuraminidase imhando yemishonga inoshandiswa mukurapa hutachiona hwehutachiona. Mushonga uyu unogona kushandiswa muzvidzidzo zvekuwanikwa kwemishonga, zvichibatsira vaongorori kuona nekuongorora zvinogona kudzivirira neuraminidase.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C21H26NNaO11
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	76204-02-9
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.