(2S,4S)-1-Boc-4-Aminopyrrolidine-2-carboxylic acid CAS:132622-66-3

(2S,4S)-1-Boc-4-aminopyrrolidine-2-carboxylic acid inoshanda sechikamu chakakosha mukugadzirwa kwemakemikari akaomarara, anoshanda mumuviri ane mukana wekushandiswa mumishonga. Hunhu hwayo hwechiral uye chimiro chayo chakasiyana zvinoiisa sechinhu chakakosha pakugadzirwa kwemakemikari e-enantiopure, ayo akakosha mukugadzirwa kwemishonga. Nekubatanidza ichi chivakwa mumamorekuru, vaongorori vanogona kutsvaga mishonga mitsva inotarisa nzvimbo dzekurapa dzakadai semishonga inorwisa mavhairasi, antineoplastics, kana matambudziko etsinga dzepakati. Mukemikari yemishonga, iyi kemikari inogona kushanda senzvimbo yekutanga yekugadzira mishonga inogona kushandiswa, ichishandisa stereochemistry yayo kugadzirisa mashandiro ebhayoloji uye pharmacokinetic properties. Kudzivirirwa kweBoc kweboka reamino kunopa kutonga pamusoro pe reactivity uye kusarudza panguva yekushandurwa kwemakemikari kunotevera, zvichigonesa kuvaka zvivakwa zvakasiyana-siyana zvemakemikari. Uyezve, munzvimbo dzedzidzo nemaindasitiri, vaongorori vanogona kushandisa iyi chivakwa kugadzirira maraibhurari ezvigadzirwa zvakasiyana-siyana zvezvidzidzo zvehukama hwechimiro-chiitiko, zvichiita kuti zvikwanise kuzivikanwa kwemakemikari emutobvu ane mhedzisiro yebhayoloji inodiwa. Basa rayo mukugadzirwa kwemakemikari rinowedzera kugadzirwa kwemishonga inopindirana uye kugadzirwa kwenzira itsva dzekugadzira, kuratidza kushanda kwayo kwakakura muzvikamu zvesainzi. Zvose, (2S,4S)-1-Boc-4-aminopyrrolidine-2-carboxylic acid inoita basa guru mukutsvaga kuwanikwa kwemishonga mitsva uye kugadzira mishonga isina kuenzana, zvichipa chikuva chekugadzirwa kwemamorekuru akasiyana-siyana anoshanda nehupenyu uye mishonga yepakati.