Adefovir CAS:106941-25-7

Adefovir inoita basa guru mukurapa hepatitis B isingaperi, inoshanda semushonga unokosha wekurwisa mavhairasi. Inoshandiswa kudzivirira kudzokororwa kwehutachiona hwehepatitis B (HBV) nekukanganisa DNA polymerase yehutachiona, zvichizopedzisira zvaderedza kugadzirwa kweHBV DNA. Izvi zvinobatsira mukuderedza huwandu hwehutachiona muvarwere vane hepatitis B isingaperi, nokudaro zvichibatsira kuderedza kukuvara kwechiropa nekudzivirira kufambira mberi kwechirwere. Hunhu hweAdefovir hwekurwisa mavhairasi hunoita kuti ive chinhu chakakosha mukurapa hepatitis B isingaperi, zvichipa sarudzo yakakosha yekurapa kune varwere vane chirwere ichi. Uyezve, Adefovir yakaongororwa nekuda kwekushandiswa kwayo mukurapa mamwe mavhairasi, kusanganisira hutachiona hweHIV (human immunodeficiency virus) neherpesviruses. Maitiro ayo senucleotide analog reverse transcriptase inhibitor inoita kuti ishandiswe mukurapa hutachiona hweHIV. Pamusoro pezvo, kushanda kwayo mukurwisa mamwe mavhairasi eherpes kunoratidza kuti inogona kushandiswa mukurapa hutachiona hweherpesvirus, zvichibatsira mukutsvaga nzira itsva dzekurapa zvirwere izvi. Kugadzirwa uye kuongororwa kweAdefovir kunoratidza kukosha kwayo mukurapa mavhairasi uye kutonga zvirwere zvinotapukira. Basa rayo mukurapa chirwere chehepatitis B chisingaperi uye kugona kwayo kuferefeta mukurapa mamwe hutachiona hwehutachiona zvinosimbisa kukosha kwayo mukurapa kwehutachiona, pharmacology, uye mishonga yekiriniki. Kuenderera mberi kwekutsvaga uye kuongororwa kwekiriniki kweAdefovir kunosimbisa kuedza kuri kuenderera mberi kwekuwedzera mashandisirwo ayo ekurapa uye kuwedzera mipiro yayo muzvirongwa zvekurwisa hutachiona. Mukupfupisa, kushandiswa kweAdefovir kunosanganisira basa rayo guru mukurapa chirwere chehepatitis B chisingaperi uye mashandisirwo ayo anogona kuitwa mukurapa mamwe hutachiona hwehutachiona, zvichiratidza kukosha kwayo mukurapa kwehutachiona hwehutachiona uye kutsvagurudza kwezvirwere zvinotapukira. Hunhu hwayo hwemishonga uye nzira dzekudzivirira hutachiona dzinoiisa semushonga unokosha mumunda wehutachiona, zvichipa nzira dzinovimbisa dzekuvandudza kurapwa kunoshanda kwezvirwere zvakasiyana-siyana zvinokanganisa hutano hwepasi rose.