Adenosine CAS:58-61-7

Muindasitiri yemishonga, adenosine inoshandiswa nekuda kwehunhu hwayo hwemishonga, kunyanya mukurapa mamwe ma arrhythmia emwoyo. Inopihwa netsinga kuti idzorere rhythm yemoyo yakajairika panguva ye supraventricular tachycardia episodes. Uyezve, mhedzisiro ye adenosine ye vasodilatory inobatsira mukushandiswa kwayo mukuongorora kwakadai sekuongororwa kwekushushikana kwechirwere che coronary artery, uko inobatsira kukurudzira kudzora kuyerera kweropa mucoronary kuti iongorore myocardial perfusion. Kunze kwekushandiswa kwemwoyo, adenosine inoshanda sechinhu chakakosha mukugadzirwa kwemishonga, nevaongorori vachiongorora kugona kwayo mukugadzirisa mamiriro akasiyana kubva kuzvirwere zvinokanganisa tsinga kusvika kukenza. Kubatanidzwa kwayo mukugadzirisa kuburitswa kwe neurotransmitter uye kushanda kwe synaptic kwakaita kuti kuferefetwe mishonga yakavakirwa pa adenosine yezvirwere zvetsinga uye mamiriro epfungwa. Uyezve, adenosine uye mamwe ma analogue ayo anodzidzwa kuti aone mhedzisiro yayo yekudzivirira muviri, ine zvazvinoreva kuzvirwere zve autoimmune, kuzvimba, uye mushonga we transplant. Nekutarisa adenosine receptors, vaongorori vanovavarira kushandisa hunhu hwe adenosine hwekudzivirira muviri uye hwekudzivirira kuzvimba sehwaro hwekugadzira mishonga mitsva. Muchidimbu, mabasa akawanda e adenosine anosanganisira kushandiswa kwesimba mumuviri, kushanda kwemwoyo, kufambiswa kwetsinga, uye kugadziriswa kwesimba remuviri zvinosimbisa kukosha kwayo mukutsvagisa mishonga uye kushandiswa kwekurapa, zvichipa nzira yakapfuma yekufambisa mberi kupindira mune zvehutano uye kuwedzera kunzwisisa kwedu mashandiro emasero nemuviri.