Amphotericin B – Jekiseni reCAS:1397-89-3

Jekiseni reAmphotericin B rinoshandiswa pakurapa hutachiona hwakakomba hwefungus hwakadai se candidiemia, invasive aspergillosis, cryptococcal meningitis, uye mucormycosis, kunyanya muvarwere vane immune system isina simba kana avo vane immune system isina simba. Nekuda kwekushanda kwayo nesimba kwe fungus, jekiseni reAmphotericin B rinowanzoonekwa senzira yekutanga yekurapa hutachiona hwefungus hwakakomba mumuviri. Nyanzvi dzezvehutano dzinopa amphotericin B netsinga, dzichinyatsotarisa varwere panguva yekuisa mushonga kuti dzigadzirise migumisiro yakaipa, kusanganisira fivha, dzihwa, uye maitiro ane chekuita nekuisa mushonga. Chiyero uye nguva yekurapa kweAmphotericin B zvakagadzirirwa zvichienderana nehutachiona hwefungus, mamiriro emurwere, uye chero kusashanda zvakanaka kwenhengo dziri pasi. Zvichienderana nehutachiona hwayo uye mukana wekusagadzikana kwe electrolyte, kunyatsoongorora mashandiro eitsvo uye mazinga e electrolyte kwakakosha panguva yekurapwa kweAmphotericin B. Mafuta eAmphotericin B anogona kushandiswa kuderedza kukuvadza kweitsvo uye maitiro ane chekuita nekuisa mushonga ane chekuita neamphotericin B deoxycholate. Kugara uchitarisa migumisiro yakaipa, yakadai sekutadza kushanda zvakanaka kweitsvo uye hypokalemia, pamwe chete nerubatsiro rwakakodzera, zvinobatsira kuchengetedza kuchengetedzeka uye kushivirira kwekurapa kweamphotericin B. Vanopa hutano vanoongorora nokungwarira mabhenefiti ekurapwa vachienzanisa nenjodzi dzinogona kuitika, vachiona kuti varwere vanowana kurapwa kwakakodzera kwefungus uku vachideredza migumisiro yakaipa. Nekutarisa zvinobudirira hutachiona hwefungus hwakakomba mumuviri, jekiseni reamphotericin B rinoita basa rakakosha mukugadzirisa mamiriro ezvinhu anotyisidzira hupenyu uye kupa nzira dzekurapa kune varwere vanotarisana nezvirwere zvefungus zvakaoma.