Ansamycin CAS:72559-06-9

MaAnsamycin, akadai seRifamycins, anoshandiswa zvakanyanya mukurapa kurapa hutachiona hwakasiyana-siyana hwebhakitiriya, kusanganisira TB, maperembudzi, uye mamwe marudzi ehutachiona hwestaphylococcal nestreptococcal. Rifampin, rifamycin inozivikanwa, inowanzo shandiswa sechikamu chekurapa kwakabatana kweTB nedzimwe hutachiona hwemycobacterial. Maitiro ekushanda kweansamycins anosanganisira kusunganidza RNA polymerase yebhakitiriya, nokudaro ichidzivisa kunyorwa kwemushonga uye pakupedzisira ichitungamira kurufu rwemasero ebhakitiriya. Maitiro aya akasiyana anoita kuti ansamycins ishande kurwisa mabhakitiriya akasiyana-siyana eGram-positive neGram-negative. Vanopa hutano vanofungisisa zvinhu zvakaita serudzi rwehutachiona, nhoroondo yekurapa kwemurwere, uye mhedzisiro yekuongororwa kwehutachiona hwebhakitiriya pavanopa ansamycins. Kuyera kwakakodzera, nguva yekurapwa, uye kutarisa migumisiro inogona kuitika zvakakosha kuti pave nekuwedzera mabhenefiti ekurapa ukuwo zvichideredza njodzi dzine chekuita nekushandiswa kwemishonga inorwisa mabhakitiriya. Migumisiro yakaipa ine chekuita neansamycins inogona kusanganisira kusagadzikana kwemudumbu, kukuvadza masero eropa, uye hypersensitivity reactions. Kugara uchitarisa mashandiro echiropa uye kuongorora zviratidzo zvemabatiro akashata kunobatsira kuona kuti ansamycins inoshandiswa zvakachengeteka uye zvinobudirira mukurapa hutachiona hwehutachiona. Kazhinji, ansamycins imhando inokosha yemishonga inorwisa mabhakitiriya ine mashandisirwo akasiyana-siyana mukurapa hutachiona hwehutachiona. Nekushandisa kwakakodzera uye kutarisa, nyanzvi dzehutano dzinogona kushandisa hunhu hwemishonga inorwisa mabhakitiriya yeansamycins kurwisa hutachiona zvinobudirira uye kuvandudza mhedzisiro yemurwere.