Avibactam sodium CAS:1192491-61-4

Avibactam sodium inoshandiswa mukurapa semushonga unodzivirira beta-lactamase kuti udzorere kushanda kwemamwe maantibiotics kurwisa mabhakitiriya asingaurayiwi nemishonga yakawanda. Inowanzo sanganiswa nemishonga inorwisa mabhakitiriya yakaita seceftazidime kugadzira musanganiswa wemishonga inorwisa mabhakitiriya akawanda ane Gram-negative, kusanganisira Enterobacteriaceae nePseudomonas aeruginosa. Vanachiremba vanopa mishonga inorwisa mabhakitiriya ine avibactam sodium yezvirwere zvakaoma zvemudumbu, hutachiona hwemudumbu, pneumonia inowanikwa muchipatara, nezvimwe zvirwere zvakakomba zvinokonzerwa nehutachiona husingaurayiwi nemishonga inorwisa mabhakitiriya. Kuwedzera avibactam sodium kunobatsira kukunda nzira dzekudzivirira mabhakitiriya, zvichidzoreredza kushanda kwemishonga inorwisa mabhakitiriya mukurwisa hutachiona hwakaoma kurapa. Mishonga inosanganisira avibactam sodium inogadzirwa zvichibva pahutachiona chaihwo, zvinhu zvinokanganisa murwere, mhedzisiro yekuongororwa kwehutachiona, uye musanganiswa wemishonga inorwisa mabhakitiriya inoshandiswa. Kutarisa kwakanyatsonaka kwemhinduro yekurapa, maitiro ehutachiona, uye mhedzisiro yakaipa inogona kuitika kwakakosha kuti kuve nechokwadi chemhedzisiro yakanaka yekurapa uye kuderedza njodzi yekukundikana kwekurapa. Migumisiro yakaipa inobatanidzwa nemishonga inorwisa mabhakitiriya ine avibactam sodium inogona kusanganisira kusagadzikana kwemudumbu, hypersensitivity reactions, uye njodzi dzine chekuita nekushandiswa kwemishonga inorwisa mabhakitiriya panguva imwe chete. Vanopa hutano vanofanirwa kufunga nezvehunhu hwemurwere wega wega uye kusangana kwemishonga pavanopa mishonga iyi kuti vawedzere kushanda zvakanaka uye kuchengetedzeka kwekurapa. Nekubatanidza avibactam sodium nemishonga inorwisa mabhakitiriya yakakodzera, nyanzvi dzehutano dzinogona kugadzirisa hutachiona hwemabhakitiriya husingarapike nemishonga yakawanda, dzichipa varwere dzimwe nzira dzekurapa uye dzichivandudza mhedzisiro yekiriniki mukutarisira zvirwere zvinotapukira zvakaoma.