beta-Nicotinamide adenine dinucleotide trihydrate CAS:53-84-9

Beta-Nicotinamide adenine dinucleotide trihydrate, inozivikanwawo seβ-NAD+, i coenzyme inowanikwa mumasero ese mapenyu. Inoita basa rakakosha mukushandiswa kwemasero nekufambisa maerekitironi panguva ye redox reactions.β-NAD+ inobatanidzwa mukugadzirwa kwesimba, ichishanda se coenzyme mumabasa akawanda akakosha ekugadzirisa muviri, anosanganisira glycolysis, TCA cycle, uye oxidative phosphorylation. Inobatanidzwawo mumaitiro ekugadzirisa DNA uye inoshanda semorekuru inoratidza zviratidzo munzira dzakasiyana dzemasero.β-NAD+ inokosha pakuchengetedza hutano hwese hwemasero uye kushanda kwawo.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Kugadzirwa kwesimba: β-NAD+ chinhu chakakosha mukushandura chikafu kuita simba. Inoshanda se coenzyme mukufema kwemasero, ichibatsira kutamiswa kwemaerekitironi kubva kuma metabolites kuenda kune cheni yekufambisa maerekitironi. Kutamiswa uku kwemaerekitironi kwakakosha pakugadzirwa kweATP, inova ndiyo simba guru remasero.

Kugadziriswa kweDNA: β-NAD+ inobatanidzwa mukugadzirisa DNA. Inoshanda sechikamu chema enzymes akadai sePARPs (Poly [ADP-ribose] polymerases), ayo anoshandisa β-NAD+ kugadzirisa DNA yakakuvara mukupindura kushushikana kwakasiyana-siyana kwemasero kwakadai sekukuvadzwa kweDNA kunokonzerwa nemwaranzi, chepfu, kana kushushikana kwe oxidative.

Kupa zviratidzo mumasero: β-NAD+ yave chinhu chakakosha chinopa zviratidzo chinoshanda munzira dzakasiyana dzemasero. Inogona kushanda senzira yekutanga mamorekuru akasiyana-siyana ekupa zviratidzo, akadai seADP-ribose neNAADP, ayo anodzora kuburitswa kwecalcium uye kufambiswa kwemashoko. Pamusoro pezvo, metabolism yeβ-NAD+ inogona kukanganisa kuratidzwa kwemajini, kukwegura, uye mamwe maitiro emuviri.

Mashandisirwo ekurapa: Kuwedzera β-NAD+ uye kushandurwa kwemazinga eβ-NAD+ kuri kuongororwa kuti kuonekwe kuti zvingangoshandiswa sei pakurapa. Ongororo dzichangoburwa dzinoratidza kuti kuwedzera mazinga eβ-NAD+ kunogona kuva nemigumisiro yakanaka pazvirwere zvine chekuita nekukwegura, zvirwere zvetsinga, matambudziko ekugaya chikafu, uye hutano hwemwoyo. Kunewo kutsvagurudza kuri kuenderera mberi mukushandiswa kwezvinhu zvinotangira β-NAD+, zvakaita senicotinamide riboside uye nicotinamide mononucleotide, sezvinowedzera zvinogona kuwedzera mazinga eβ-NAD+ mumuviri.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C21H27N7O14P2
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	53-84-9
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.