Bethahistinemethanesulfonate CAS:54856-23-4

Bethahistinemethanesulfonate inonyanya kushandiswa mukurapa, kunyanya nekuda kwekubatsira kwayo pakurapa zvirwere zvevestibular zvakaita sechirwere chaMeniere nezvimwe zvirwere zvine chekuita nechiyero. Chirwere chaMeniere chinosanganisira zviitiko zvekunzwa kusviba, tinnitus, uye kurasikirwa nekunzwa, zvichibva pakusagadzikana kwemvura munzeve yemukati. Kupiwa kweBethahistinemethanesulfonate kunogona kubatsira kuderedza zviratidzo izvi nekuwedzera kuyerera kweropa munzeve yemukati, nokudaro kuchidzikamisa system yevestibular uye kuderedza kuwanda uye kuoma kwezviitiko zvinosviba. Kuwedzera kune zvirwere zvevestibular, Bethahistinemethanesulfonate inogonawo kubatsira pakurapa zvimwe zvirwere zvine chekuita nekushaikwa kweropa. Nekushanda semushonga wevasodilator, inobatsira kuvandudza kuyerera kweropa mumatishu akasiyana-siyana, zvichiita kuti ibatsire varwere vane zvirwere zveropa. Kuvandudzwa uku kwekufamba kweropa kunogona kuwedzera kuendesa kweokisijeni nezvinovaka muviri kunzvimbo dzakakanganiswa, zvichikurudzira kupora uye kushanda zvakanaka. Uyezve, tsvakiridzo yakaratidza kushandiswa kunogona kuitwa kweBethahistinemethanesulfonate mukudzivirira tsinga nekuvandudza kugona kwepfungwa. Kushanda kwayo semushonga we histamine receptor agonist kunoratidza kuti inogona kuita basa mukugadzirisa kuburitswa kwema neurotransmitter, nokudaro ichipesvedzera maitiro ekuziva uye ichipa mhedzisiro yekudzivirira tsinga muzvirwere zvinoderedza tsinga. Mushonga uyu unogona zvakare kutariswa kuti ushandiswe mune dzimwe nzvimbo, senge mukurapa mamwe maitiro e allergic nekuda kwebasa rayo re histamine. Zvisinei, kushandiswa kwayo munzvimbo iyi kunoda kutsvagurudzwa kwakawanda uye kusimbiswa. Kazhinji, Bethahistinemethanesulfonate mushonga wekurapa unozivikanwa nemhedzisiro yawo yakanaka pakushanda kwe vestibular uye kutenderera kweropa, uchiratidza vimbiso mukushandiswa kwakasiyana-siyana kwekurapa kwakatarisana nekuvandudza hupenyu hwemurwere.