Boc-Nle-OH·DCHA CAS:21947-32-0

Boc-Nle-OH·DCHA inoshandiswa zvakanyanya mukugadzirwa kwepeptide yakasimba kugadzira mapeptide akagadzirwa nemaitiro akasiyana uye mashandiro. Senzira yakachengetedzwa yenorleucine, inogonesa kuiswa kwenorleucine residues mu peptide chain iri kukura, ichidzivirira kusawirirana kusingadiwe uye ichibvumira kugadzirwa kwepeptide dzakaoma dzine hunhu hwakagadzirirwa. Mu bioconjugation uye chemistry biology, Boc-Nle-OH·DCHA inoshanda sechivako chinoshanduka-shanduka chekugadzira mapeptide anoshanda, ma probes ane labeled, uye peptide-based therapeutics. Kushandiswa kwayo kunogonesa kugadziriswa kwakanyatsojeka kwepeptides nemapuroteni, zvichibatsira kukura kwemamorekuru anoshanda akawanda ane kugadzikana kwakawedzerwa, chinangwa chaicho, kana kugona kwekufungidzira kwezvishandiso zvakasiyana-siyana zve biomedical. Uyezve, mukuwana mishonga nekuvandudza kurapa, Boc-Nle-OH·DCHA inoshandiswa kugadzira peptide conjugates uye modified peptides ine pharmacokinetic profiles yakagadziridzwa uye mabasa e biological. Kugadziriswa uku kunogona kuwedzera kushanda, kusarudza, uye kuendeswa kwemishonga yakavakirwa papeptide, zvichibatsira mukufambira mberi mukurapa kwakaringana uye kurapwa kwakanangana. Kazhinji, kuvimbika uye kushanduka-shanduka kweBoc-Nle-OH·DCHA mukugadzirwa kwepeptide uye bioconjugation kunoita kuti ive chishandiso chakakosha chekufambira mberi mukutsvaga mishonga, makemikari ebhayoloji, uye proteomics, zvichipa mikana yakasiyana-siyana yekugadzira mashandisirwo matsva ekurapa.