Candesartan CAS:139481-59-7 Mugadziri Mutengesi

Candesartan is an angiotensin II receptor I (AT1) antagonist, IC50s=1.12 uye 2.86 nM yebovine adrenal cortex uye tsuro aorta zvakateerana.Selectively inhibits angiotensin II-induced contraction ye tsuro aortic strips isina mhedzisiro pane imwe contraction in nodpiine , KCl, serotonin, PGF2αkana endothelin.

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Candesartan inosarudza AT1 (angiotensin II receptor 1) anopikisa.Kupikisa kweangiotensin receptors kunodzivisa vasoconstriction uye kugadzirwa kwealdosterone, zvichiita kuti kuderera kwemvura uye sodium concentration muplasma yeropa.Inoratidza antihypertensive mhedzisiro mumhando dzemhuka.Inoshandiswa mukurapa congestive heart failure, se antihypertensive.Candesartan haikanganisi kushanda kwesero kana kuwanda asi inowedzera kutaura kweVEGF uye interleukin-8 muchimiro chetsika cheKU-19-19 masero.Candesartan (0.1 nM) inogona kuderedza maximal contractile mhinduro kune angiostensin II ne50%.

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Composition	C24H20N6O3
Assay	99%
Chitarisiko	Upfu chena
CAS Nha.	139481-59-7
Packing	1KG 25KG
Sherufu Hupenyu	2 years
Storage	Chengetedza munzvimbo inotonhorera uye yakaoma
Certification	ISO.