Concanavalin A CAS:11028-71-0 Mutengo wemugadziri

Concanavalin A (Con A) ipuroteni inonzi lectin, inova mhando yeprotein inogona kubatana zvakananga nemamwe mamorekuru eshuga. Inotorwa kubva mumbeu dzemuti wejackbean (Canavalia ensiformis).

Con A ine hukama hwakakura nemannose neglucose sugar residues uye inogona kubatana neglycoproteins neglycolipids dzine shuga idzi. Inogadzira complexes dzinodzoreka nemamorekuru aya kuburikidza nekudyidzana kwemacarbohydrate neprotein.

Nekuda kwekugona kwayo kusunga shuga, Con A inowanzoshandiswa mukutsvagisa kwezvipenyu uye kuongororwa kwezvirwere. Yave ichishandiswa zvakanyanya sechishandiso chekudzidza maglycoprotein, shuga iri pamusoro pemasero, uye kudyidzana kwakavakirwa pamakabhohaidhiretsi. Inogona kushandiswa kupatsanura nekuchenesa maglycoprotein nekushandisa affinity chromatography, pamwe nekuona nekuyera huwandu hweshuga hwakati wandei pamusoro pemasero kana mumisanganiswa yakaoma.

Con A inewo simba rekudzivirira muviri. Inogona kukurudzira kushanda uye kuwanda kwemamwe masero ekudzivirira muviri, akadai seT lymphocytes, uye yakaongororwa kuti inogona kushandiswa sei mukurapa immunotherapy uye majekiseni.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Kuungana kwemasero: Chimwe chezvinhu zvinonyanya kukosha zvinokonzerwa neCon A kugona kwayo kukonzera kuungana kwemasero. Izvi zvave zvichibatsira pakudzidza kubatana kwemasero uye kudyidzana kwemasero pamusoro pemasero.

Kupatsanurwa kweGlycoprotein: Con A inobatanidza zvakananga nemaglycoprotein ane terminal mannose uye glucose residues. Hunhu uhwu hwakashandiswa kupatsanura nekuchenesa maglycoprotein kubva mumisanganiswa yakaoma, senge biological fluids kana cell lysates, nekushandisa Con A affinity chromatography.

Kuonekwa kweGlycoproteins: Con A inogona kushandiswa kuona nekuyera maglycoproteins ari musampuli. Nekushandisa Con A yakabatana nema fluorescent kana enzymatic tags, zvinokwanisika kuona kana kuyera huwandu hwemaglycoproteins ari musampuli kuburikidza ne fluorescence microscopy kana enzyme-linked immunosorbent assay (ELISA) techniques, zvichiteerana.

Kunyora Mazita Pamusoro Pemasero: Nekuda kwekuda kwayo shuga pamusoro pemasero, Con A inogona kushandiswa kunyora mazita emhando dzakasiyana dzemasero kana kudzidza maitiro eglycosylation pamusoro pemasero. Con A yakabatana ne fluorophores kana mamwe ma tag inobvumira kuona nekuongorora masero kuburikidza nenzira dzakadai se flow cytometry kana fluorescence microscopy.

Kugadzirisa Dziviriro yeMadziviriro: Con A ine simba rekugadzirisa dziviriro yemuviri uye inogona kukanganisa mashandiro emasero edziviriro yemuviri. Inogona kukurudzira kushanda uye kuwanda kweT lymphocytes, zvichikonzera kugadzirwa kwemacytokine nedzimwe mhinduro dzedziviriro yemuviri. Hunhu uhwu hwakaongororwa mukurapa nekugadzira majekiseni, uko Con A yakashandiswa kusimudzira mhinduro dzedziviriro yemuviri kana kugadzirisa kushivirira kwedziviriro yemuviri.

Chishandiso Chekutsvaga: Con A chishandiso chinoshandiswa zvakanyanya muzvikamu zvakasiyana-siyana zvekutsvagisa zvipenyu. Chave chichishandiswa kudzidza kudyidzana kwemacarbohydrate nemapuroteni, kubatana kwemasero, maitiro eglycosylation, uye mhinduro dzemuviri. Kukwanisa kwayo kubatana neshuga chaiyo kunoita kuti ive yakakosha pakudzidza nekushandura maglycoprotein nemaglycolipid.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C15H24
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	11028-71-0
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.