Delamanid CAS:681492-22-8

Delamanid mushonga unorwisa mabhakitiriya unonzi diarylquinoline derivative, unonyanya kushandiswa mukurapa chirwere cheTB chisingadi mishonga yakawanda (MDR-TB). Unoshanda nekutarisa mycobacterial ATP synthase, zvichikonzera kukanganiswa kwekugadzirwa kwesimba mumabhakitiriya anokonzera chirwere cheTB. Delamanid inoonekwa semushonga wechipiri weMDR-TB kune vanhu vane chirwere cheTB vasingadi mishonga yemhando yekutanga. Mushonga uyu unowanikwa muchimiro chemapiritsi uye unowanzo kunyorerwa sechikamu chemishonga yakakwana yekurwisa hutachiona hweTB husingadi mishonga.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro:

Delamanid chishandiso chakakosha chemishonga mukurapa TB isingarapike nemishonga yakawanda, rudzi rwakakomba rweTB rusingarapike nemishonga yekutanga. Inowanzo batanidzwa mumishonga yeMDR-TB kuti ivandudze mhedzisiro yekurapa uye kuderedza njodzi yekukura kwekusarapike nemishonga. Vanopa hutano vanopa delamanid pamwe chete nemimwe mishonga yemutsara wechipiri yekurwisa TB zvichibva pane zvinhu zvinokanganisa murwere mumwe nemumwe, kusanganisira huwandu hwekusarapike nemishonga, nhoroondo yekurapwa kare, uye hutano hwese. Mushonga uyu unowanzo pihwa nemuromo muchimiro chemapiritsi, uye huwandu hwemushonga uye nguva yakatarwa zvinoenderana nezvinodiwa nemurwere wega wega. Varwere vari kurapwa nedelamanid vanokurudzirwa kutevedzera zvakanyanya chirongwa chakarairwa, sezvo kutora mishonga nguva dzose kwakakosha kuti vabudirire mukurapa uye kuderedza njodzi yekukundikana kwekurapwa. Kugara vachitarisa migumisiro inogona kuitika, senge kusagadzikana kwemudumbu kana shanduko mukushanda kwechiropa, kwakakosha panguva yekurapwa. Kurapa neDelamanid kunowanzo tangwa uye kutariswa nenyanzvi dzehutano dzine ruzivo mukutarisira nyaya dzeTB isingarapike nemishonga. Kushanda pamwe chete pakati pechikwata chehutano nemurwere kwakakosha kuti kuve nechokwadi chekutevedzera kurapwa, kutarisa kufambira mberi, uye kugadzirisa chero kunetseka kana matambudziko nekukurumidza. Mukupedzisa, delamanid ine basa guru mukurwisa TB isingarapike nemishonga yakawanda, ichipa varwere nevanoona nezveutano nzira inoshanda yekurapa chirwere ichi chinotapukira uye kudzivirira kupararira kwacho munharaunda.

Muenzaniso weChigadzirwa:

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C25H25F3N4O6
Kuyedza	99%
Chitarisiko	upfu chena
Nhamba yeCAS	681492-22-8
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.