Duloxetine HCL CAS:136434-34-9 Mugadziri Mutengesi

Duloxetine HCL imhando yemunyu yeantidepressant drug duloxetine.Yakagadzirwa zvakabudirira neEli Lilly Company.Iyo pharmacological effect yakafanana ne duloxetine.Duloxetine hydrochloride rudzi rutsva rwekusarudza dual inhibitor ye5 hydroxy trptamine (5-HT) uye norepinephrine reuptake, uye nokudaro ine antidepressant effect, uyewo ine inhibitory effect pakurwadziwa kwepakati.Hunhu hwayo hwemishonga huri kukwanisa kuvharidzira kudzokororwa kweneuronal pre-synaptic membrane pa 5-hydroxy trptamine uye norepinephrine asi panzvimbo pacho kuve nekushomeka kwekudzivirira pakutorazve kwe dopamine.Duloxetine hydrochloride inoratidzwa nokuda kwekuora mwoyo uye inoshanda mukurapa zvose zvinopera uye zvisingatauri kuora mwoyo pamwe nekunzwa kwemarwadzo ane chokuita nekuora mwoyo.Iine mushonga wekurapa we60mg/d ~ 120mg/d nekuchengetedzwa kwakanaka uye kushomeka kwemaitiro akashata ane zvinowanzoitika zvakashata senge kusvotwa, kuoma kwemuromo, kuvimbiswa, kusada kudya, kuneta, kurara, uye kuwedzera dikita.Chimwe chinoratidza kurwadziwa kunokonzerwa neshuga yeuropathy.