Duloxetine HCL CAS:136434-34-9 Mugadziri weMugadziri

Duloxetine HCL imhando yemunyu yemushonga unoderedza kushushikana kwemuviri wemudumbu we duloxetine. Yakagadzirwa zvinobudirira neEli Lilly Company. Mhedzisiro yayo yemishonga yakafanana neduloxetine. Duloxetine hydrochloride imhando itsva ye5 hydroxy trptamine (5-HT) uye norepinephrine reuptake, uye nekudaro ine simba rekuderedza kushushikana, ukuwo ichiita kuti pave nemhedzisiro yekudzivirira kurwadziwa kwepakati. Hunhu hwayo hwemishonga kukwanisa kudzivirira kudzoserwa kwemasero eropa e-neuronal pre-synaptic pa5-hydroxy trptamine ne norepinephrine asi panzvimbo pezvo ine mhedzisiro shoma yekudzivirira pakudzoserwa kwedopamine. Duloxetine hydrochloride inoratidzwa pakuora mwoyo uye inoshanda mukurapa kusuruvara kwemuviri uye kusiri kwemuviri pamwe nekunzwa kurwadziwa kunoenderana nekuora mwoyo. Ine dose yekurapa ye60mg/zuva ~ 120mg/zuva ine kuchengetedzwa kwakanaka uye ine mhedzisiro shoma yemigumisiro yakaipa ine mhedzisiro yakaipa yakafanana nekusvotwa, muromo wakaoma, kuvimbiwa, kushaya chido chekudya, kuneta, hope, uye kudikitira kwakawanda. Chimwe chiratidzo kurwadziwa kunokonzerwa nechirwere cheshuga.