dUMP, 2′-Deoxyuridine-5′-monophosphate, disodium salt CAS:42155-08-8 Mufananidzo Unoratidzwa

dUMP, 2′-Deoxyuridine-5′-monophosphate, munyu we disodium CAS:42155-08-8

2′-Deoxyuridine-5′-monophosphate (dUMP) chinhu chinobva mu nucleotide chinobatanidzwa mukugadzirwa nekugadzirisa DNA. Inoshanda senzira yekutanga dTTP (deoxythymidine triphosphate), inova chinhu chinodiwa pakugadzirwa kweDNA. dUMP chinhu chakakoshawo mukugadzirwa kwe thymidylate, uko inoshandurwa kuita dTMP (deoxythymidine monophosphate) ne enzyme thymidylate synthase. Kushandurwa uku kwakakosha pakuchengetedza nucleotide balance uye DNA perfection zvakanaka mukati memasero.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Kugadzirwa kweDNA: dUMP inoshanda senzira yekutanga kwe deoxythymidine triphosphate (dTTP), iyo inokosha pakudzokororwa kweDNA. Kushandurwa kwe dUMP kuita dTMP idanho rakakosha mukugadzirwa kwe thymidine nucleotides, iyo inokosha pakudzokororwa kwakarurama kwezvinhu zvemajini panguva yekupatsanurwa kwemasero.

Kugadzira masero mumasero: dUMP ndiyo substrate ye enzyme inonzi thymidylate synthase, iyo inokonzeresa kushandurwa kwe dUMP kuita dTMP. Maitiro aya akakosha pakuchengetedza nucleotide balance yakakwana mumasero uye kuona kuti DNA replication yakavimbika.

Chinangwa Chemushonga Unodzivirira Kenza: Thymidylate synthase, iyo enzyme inobatanidzwa mukushandurwa kwedUMP kuita dTMP, inyanzvi inoshandiswa pakurapa kenza. Kudzivisa thymidylate synthase kunogona kukanganisa kugadzirwa kweDNA uye kuwanda kwemasero, zvichiita kuti ive imwe yenzira dzekurapa chemotherapy.

Chishandiso Chekutsvaga: dUMP inoshandiswa mukutsvagisa kwebiochemical uye molecular biology sechikamu chekudzidza mashandiro ekugadzirwa kweDNA, kugadziriswa, uye metabolism ye nucleotide. Inoshandiswawo mukuyedza enzymes kuongorora mashandiro e thymidylate synthase nema enzymes ane hukama.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C9H14N2NaO8P
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	42155-08-8
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.