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Lasmiditant CAS:439239-90-4
Lasmiditan, inotengeswa pasi pezita rekuti Reyvow, imushonga mutsva wemishonga wakagadzirirwa kuderedza kurwiswa kwemigraine muvanhu vakuru. Iri muboka rema agonists ekusarudza serotonin receptor, kunyanya anotarisa mhando ye5-HT1F receptor. Maitiro aya ekuita anosiyanisa Lasmiditan nekurapa kwemigraine kwechinyakare, sezvo isingakonzere kuvharwa kweropa, zvichiita kuti ive yakakodzera varwere vane njodzi dzemwoyo.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone ikemikari inozivikanwa nekushandiswa kwayo kwakasiyana-siyana mukugadzirwa kwezvinhu zvipenyu uye makemikari ekubatanidza. Kugadzirwa kwayo kunosanganisira kuita kweN-methylcarbamoyl chloride ne2-chloroacetohydrazide, zvichikonzera kemikari ine hunhu hwakasiyana hwemaumbirwo uye mashandiro. Kemikari iyi inoratidzwa nekukwanisa kwayo kugadzira macomplexes ane maion akasiyana-siyana esimbi, zvichiita kuti ive yakakosha muzvidzidzo zvekemikari yekubatanidza. Pamusoro pezvo, mapoka ayo ecarbonyl neamidrazone anobatsira mukuita kwayo uye mabasa ayo emishonga, ayo ari nzvimbo dzinonyanya kufarirwa nekutsvaga.
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Lasmiditan HCl CAS:613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) mushonga unozivikanwa nebasa rawo mukurapa kurwiswa kwemigraine kwakanyanya muvanhu vakuru. Yakagadzirwa semushonga unosarudza we serotonin receptor agonist, kunyanya wakanangana ne 5-HT1F receptor subtype, Lasmiditan HCl inomiririra kufambira mberi kukuru mukurapa migraine nekuda kwekushanda kwayo kwakasiyana uye kushanda kwayo zvakanaka.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, inozivikanwawo seaminopyridine methylpiperidone, ikemikari ine zvayakanakira zvikuru mukurapa kemikari uye mukutsvaga mishonga. Yakagadzirwa kuburikidza nekuita kwe6-aminopicolinic acid ne1-methylpiperidin-4-one, iyi kemikari inoratidza zvinhu zvakasiyana-siyana zvinobatsira mukushanda kwayo kwemishonga uye kushanda kwayo kwakasiyana-siyana.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-Quinuclidinol, inozivikanwawo sequinuclidinol, chinhu chakakosha muongororo yemakemikari echisikigo uye mishonga nekuda kwekusiyana kwemaumbirwo ayo uye mashandisirwo ayo akasiyana-siyana. Ichi chinhu chiral chinobva kuquinuclidine uye chinoratidza hunhu hwakasiyana hwemakemikari nemishonga hwakakwezva kutariswa muzvikamu zvakasiyana zvesainzi.
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ZVINONYANYA KUSHANDISWA NE APREPITANT CAS:171482-05-6
Mishonga yeAprepitant inoita basa guru mukugadzirwa kwemishonga yeaprepitant, mushonga une simba weneurokinin-1 (NK1) receptor antagonist unoshandiswa zvikuru mukudzivirira kuda kurutsa nekusvotwa kunokonzerwa nechemotherapy (CINV). Mishonga iyi inonyanya kukosha munzira yekugadzira ine matanho akawanda inotungamira kukugadzirwa kwekupedzisira kweaprepitant. Aprepitant pachayo inozivikanwa nekushanda kwayo mukurapa CINV, ichipa zororo guru kuvarwere vari kurapwa nechemotherapy. Kugadzirwa kweaprepitant kunosanganisira matanho akati wandei akakosha, uye mishonga yepakati inoshanda semabhuroko anogonesa kugadzirwa kwakanaka kwemushonga uyu unokosha wekurapa.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
2,4,6-Trifluorobenzoyl chloride, inozivikanwawo se trifluorobenzoyl chloride, ikemikari yakakosha inokosheswa nekuda kwekushandiswa kwayo kwakasiyana-siyana mukugadzirwa kwezvinhu zvipenyu uye maitiro emaindasitiri. Yakagadzirwa kuburikidza ne chlorination ye 2,4,6-trifluorobenzoic acid, iyi kemikari inoratidza hunhu hwakasiyana hwekemikari hunobatsira mukushandiswa kwayo kwakapararira munzvimbo dzakasiyana-siyana.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
4-Chloro-6-iodoquinazoline ikemikari ine fomura yemorekuru C9H5ClIN2. Inoratidzwa nekuvapo kwemaatomu echlorine neayodini akabatana nechimiro cheringi yequinazoline. Iyi kemikari inonyanya kushandiswa mukutsvagisa mishonga uye kugadzira organic nekuda kwekushandiswa kwayo mukugadzira mishonga mitsva nemamwe mamorekuru anoshanda mubiology.
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(R)-3-Quinuclinol CAS:25333-42-0
(R)-3-Quinuclinol, inozivikanwawo sequinuclidinol, chinhu chakakosha muongororo yemakemikari echisikigo uye mishonga nekuda kwekusiyana kwemaumbirwo ayo uye mashandisirwo ayo akasiyana-siyana. Ichi chinhu chiral chinobva kuquinuclidine uye chinoratidza hunhu hwakasiyana hwemakemikari nemishonga hwakakwezva kutariswa muzvikamu zvakasiyana zvesainzi.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Musanganiswa uyu (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate imorekuru yakaoma yeorganic ine hunhu hwayo hwechimiro uye hwemishonga. Iri muboka remakemikari emorphine, ayo anowanzo shandiswa mukemikari yekurapa nekuda kwemabasa avo akasiyana-siyana ehupenyu.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine ikemikari inozivikanwa nekushandiswa kwayo kwakasiyana-siyana mukugadzirwa kwezvinhu zvakasikwa uye makemikari ekurapa. Yakagadzirwa kuburikidza nekuita kwe (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone neammonia kana amine, kemikari iyi ine magadzirirwo akasiyana anobatsira mukusiyana kwebasa rayo uye mabasa ayo emishonga.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine ikemikari inozivikanwa nekushandiswa kwayo kwakasiyana-siyana mukugadzirwa kwezvinhu zvakasikwa uye makemikari ekurapa. Yakagadzirwa kuburikidza nekuita kwe1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone ine ammonia kana amine, iyi kemikari inoratidza hunhu hwakasiyana hunobatsira mukushanda kwayo kwakasiyana-siyana uye mabasa ayo ekurapa.
