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2-Hydroxyisonicotinic acid CAS:90-33-5
2-Hydroxyisonicotinic acid inobva muisonicotinic acid, inoratidzwa nekuvapo kweboka rehydroxyl panzvimbo yechipiri yepyridine ring. Iyi compound inoratidza mabasa akasiyana-siyana ehupenyu, kusanganisira simba rekurwisa mabhakitiriya uye rekudzivirira kuzvimba. Kufanana kwayo nemaumbirwo ayo nezvimwe zvinobva municotinic acid kunoita kuti ive chinangwa chinonakidza chekugadzirwa kwemishonga. Vaongorori vanga vachiongorora mashandisirwo ayo mumakemikari ekurapa, kunyanya mukurapa zvirwere zvakasiyana-siyana. Iyi compound inoshanda sechivako chekugadzira mamorekuru akaomarara uye yakwezva kutariswa muminda yekugadzira organic uye kutsvagurudza kwemishonga.
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Methyl 2-aminopyridine-4-carboxylate CAS:6937-03-7
Methyl 2-aminopyridine-4-carboxylate chinhu chinobva kupyridine chine boka reamino panzvimbo ye2 uye carboxylate ester panzvimbo ye4, ine boka remethyl rakabatana necarboxylic acid. Musanganiswa uyu unonyanya kufarira makemikari ekurapa nekuda kwemabasa ayo ehupenyu, kusanganisira hutachiona hwehutachiona uye hunodzivirira kuzvimba. Kurongeka kwakasiyana kwemapoka anoshanda kunoita kuti aite basa rayo uye ashande sechivako chinoshanda mukugadzirwa kweorganic. Tsvagiridzo inoramba ichiongorora mashandisirwo ayo mukugadzirwa kwemishonga nedzimwe nzvimbo, ichiratidza kukosha kwayo munzvimbo ye heterocyclic chemistry.
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Tofacitinib Citrate CAS:540737-29-9
Tofacitinib citrate mushonga weJanus kinase (JAK) unoshandiswa zvakanyanya kurapa rheumatoid arthritis, psoriatic arthritis, uye ulcerative colitis. Unoshanda nekudzivisa maenzymes eJAK1 neJAK3, ayo anoita basa rakakosha mukutumira zviratidzo zvema cytokines akasiyana-siyana anobatanidzwa mukuzvimba. Nekushandisa molecular formula C16H20N6O5S·C6H8O7, tofacitinib citrate yakaratidza kushanda zvakanaka mukuderedza kuzvimba uye kuvandudza hupenyu hwemurwere. Yakatenderwa kushandiswa mukiriniki munyika dzinoverengeka, tsvakiridzo iri kuenderera mberi ine chinangwa chekuongorora mashandisirwo ayo akakura ekurapa, kuchengetedzeka, uye mhedzisiro yenguva refu muzvirwere zvakasiyana-siyana zve autoimmune.
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Cyclen CAS:294-90-6
Cyclen, kana kuti 1,4,7,10-tetraazacyclododecane, imusanganiswa wepolyamine unozivikanwa nechimiro chayo chakasiyana chine maatomu mana enitrogen akabatanidzwa mumhete ine nhengo gumi nembiri. Nekushandisa molecular formula C8H16N4, cyclen inoshanda se ligand yakakosha mu coordinate chemistry nekuda kwekugona kwayo kugadzira stable complexes ne transition metals. Hunhu hwayo hwe chelating hunoita kuti ive yakakosha mukushandiswa kwakasiyana-siyana, kusanganisira medical chemistry, radiopharmaceuticals, uye supramolecular chemistry. Tsvagiridzo iri kuenderera mberi inoongorora kugona kwe cyclen muzvirongwa zvekupa mishonga uye kugadzirwa kwemishonga inotarisa, ichisimbisa kukosha kwayo mune zvese zvesainzi dzekutanga nedzinoshandiswa.
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![4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT317.png)
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane imusanganiswa webicyclic organic unoratidzwa nechimiro chawo chakasiyana chine ether linkages mbiri uye maatomu matatu eokisijeni mukati me bicyclic framework. Ne molecular formula C10H16O3, musanganiswa uyu unoratidza hunhu hwemakemikari hunonakidza nekuda kwekuvapo kwemapoka emethyl uye mashandiro e ether. Magadzirirwo awo e bicyclic anobatsira mukugadzikana uye reactivity, zvichiita kuti ive mukana wekushandiswa kwakasiyana-siyana mu synthetic organic chemistry. Tsvagiridzo inoongorora kushandiswa kwayo mukugadzirwa kwemamorekuru akaomarara uye kugona kwayo sechivako chekuvaka mumishonga nesainzi yezvinhu.
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![4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M290.png)
4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1
4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine chinhu chinogadzirwa chinozivikanwa nekushandiswa kwacho kwemishonga. Chine chimiro chakasiyana chinosanganisira pyrrolopyrimidine core, chloro substituent, uye sulfonyl moiety yakabatana neboka repara-methylphenyl. Kuumbwa uku kunogona kubatsira mukuita kwayo kwehupenyu, zvichiita kuti ive mukana wekutsvagisa munzvimbo dzakadai sekenza kana kuzvimba. Zvidzidzo zviri kuenderera mberi kuti zviongorore mashandiro ayo, kushanda kwayo, uye kuchengetedzeka, nechinangwa chekuona mashandisirwo ayo ekurapa muzvirwere zvakasiyana-siyana.
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3-Pyridinesulfonyl chloride CAS:16133-25-8
3-Pyridinesulfonyl chloride chinhu chakakosha cheorganic chine molecular formula C6H6ClN O2S. I sulfonyl chloride derivative ye pyridine, ine sulfonyl chloride functional group yakabatana nenzvimbo yechitatu ye pyridine ring. Iyi compound inonyanya kushandiswa mu organic synthesis se reagent yekupinza ma sulfonyl groups mu substrates dzakasiyana. Kushanda kwayo kunoita kuti ikwanise kutora chikamu mu nucleophilic substitution reactions, zvichiita kuti ive yakakosha mukugadzira sulfonamides nemamwe ma bioactive molecules. Uyezve, 3-pyridinesulfonyl chloride inogona kushandiswa mumishonga uye agrochemicals.
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2-Aminoisonicotinic acid CAS:13362-28-2
2-Aminoisonicotinic acid imhando yepyridine derivative, kunyanya isomer ye nicotinic acid, inoratidzwa nekuvapo kweboka reamino panzvimbo yechipiri ye isonicotinic acid structure. Ne molecular formula C6H6N2O2, iyi compound inoratidza hunhu hunonakidza hwemakemikari uye yakawana kutariswa mu medicine chemistry nekuda kwemabasa ayo e biology, kusanganisira antimicrobial uye anti-inflammatory effects. Mashandiro e amino ne carboxylic acid anogonesa shanduko dzakasiyana dzemakemikari, zvichiita kuti ive pakati pe organic synthesis. Tsvakurudzo iri kuenderera mberi inoongorora kugona kwayo kurapa, ichiratidza kukosha kwayo mukugadzirwa kwemishonga uye mamwe mashandisirwo ayo.
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2-Amino-4-cyanopyridine CAS:42182-27-4
2-Amino-4-cyanopyridine imhando yepyridine inoonekwa neboka reamino panzvimbo ye2 uye boka recyano panzvimbo ye4 yeringi yepyridine. Nekushandisa molecular formula C6H4N4, iyi compound inoratidza hunhu hunonakidza hwemakemikari uye zvinogona kuitika muhupenyu. Yakadzidzwa nekuda kwekushandiswa kwayo mukemikari yekurapa, kunyanya mukugadzirwa kwemishonga nekuda kwemhedzisiro yayo inorwisa mabhakitiriya, fungus, uye anti-inflammatory. Kuvapo kwemapoka ese ari maviri kunowedzera reactivity yayo, zvichiita kuti ive pakati pepakati mukugadzirwa kweorganic. Tsvagiridzo inoramba ichiongorora kushandiswa kwayo kwakasiyana-siyana muminda yakasiyana-siyana kusanganisira mishonga uye agrochemicals.
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2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) CAS:399017-10-8
2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) imhando yethiazole, inozivikanwa nechimiro chayo chakasiyana chinosanganisira hydroxyl group, methyl group, uye ethyl ester. Mushonga uyu wakawana kufarira mumakemikari ekurapa nekuda kwemabasa ayo ehupenyu, akadai sekudzivirira kuzvimba uye kuuraya utachiona. Munyu wehydrochloride unowedzera kunyungudika uye kugadzikana, zvichiita kuti ishandiswe mumishonga. Tsvagiridzo iri kuramba ichiongorora kushanda kwayo mukurapa kwakasiyana-siyana, zvichiita kuti ive yakakosha kune dzimwe dzidzo mukugadzira mishonga nekugadzirisa lead.
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3-Methyl-4-nitropyridine N-Oxide CAS:1074-98-2
3-Methyl-4-nitropyridine N-oxide chinhu chinobva kupyridine chinoratidzwa neboka remethyl panzvimbo ye3 uye boka renitro panzvimbo ye4 yeringi yepyridine, pamwe chete neboka rinoshanda reN-oxide. Chinhu ichi chinoratidza hunhu hwemakemikari uye mabasa ehupenyu, zvichiita kuti chifarirwe muminda yakasiyana-siyana yakadai sekemikari yemishonga uye agrochemicals. Kuvapo kwemapoka ese ari maviri enitro neN-oxide kunogona kuwedzera reactivity yayo uye mashandisirwo ayo mukemikari yekugadzira. Tsvagiridzo inoenderera mberi nekutsvaga mashandisirwo ekomikari iyi mukuwana mishonga nedzimwe nzira, ichiratidza kukosha kwayo mukemikari yemazuva ano yeorganic.
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(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine CAS:511534-44-4
(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine chinhu chakakosha che chiral chine boka re sulfonamide functional uye diphenylethylene backbone. Ne molecular formula C16H20N2O2S, chinhu ichi chinoita basa guru mu asymmetric synthesis uye catalysis nekuda kwekugona kwaro kugadzira chiral environments dzakagadzikana. Maumbirwo aro akasiyana anobvumira sarudzo dzakasarudzwa, zvichiita kuti rive rinokosha mukugadzirwa kwemishonga ne agrochemicals. Tsvagiridzo iri kuenderera mberi inoongorora mashandisirwo aro mu stereoselective synthesis, ichiratidza kugona kwayo se ligand mu organometallic chemistry uye kuwedzera kukosha kwayo mu synthesis yemazuva ano ye organic.
