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Ofloxacin CAS:82419-36-1
Ofloxacin mushonga unorwisa mabhakitiriya we fluoroquinolone une simba rekurwisa mabhakitiriya akasiyana-siyana ane gram-negative uye gram-positive. Unodzivirira ma enzymes eDNA gyrase ne topoisomerase IV, zvichikanganisa kudzokororwa kweDNA uye zvichikonzera kufa kwemasero ebhakitiriya. Inowanikwa mumishonga yemuromo, yemudumbu, uye yemutsinga, ofloxacin inowanzo kunyorerwa kurapa hutachiona hwakasiyana-siyana, kusanganisira hutachiona hwekufema, hutachiona hweweti, hutachiona hweganda nenyama yakapfava, uye zvirwere zvepabonde. Kushanda kwayo kwakasiyana-siyana, pharmacokinetics yakanaka, uye kushanda kwayo mukiriniki kunoita kuti ofloxacin ive sarudzo inokosha yekurapa munharaunda nemuzvipatara.
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Norfloxacin CAS: 70458-96-7
Norfloxacin mushonga we fluoroquinolone unoshanda ne broad-spectrum antimicrobial activity kurwisa mabhakitiriya e gram-negative nemamwe gram-positive. Unodzivirira bacterial DNA gyrase ne topoisomerase IV, ma enzymes akakosha anobatanidzwa mukudzokororwa kweDNA, nokudaro uchiita hutachiona. Norfloxacin inowanikwa mumishonga inonwiwa, kusanganisira mapiritsi ne suspensions, yekurapa hutachiona hwakasiyana-siyana hwebhakitiriya, hwakadai sehutachiona hwemudumbu, hutachiona hwemudumbu, hutachiona hwekufema, uye zvirwere zvepabonde. Unowanzo nyorerwa nekuda kwekushanda kwayo, kushivirira, uye nzira iri nyore yekurapa.
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Nisin CAS:1414-45-5
Nisin ipeptide yechisikigo inorwisa utachiona inogadzirwa nemamwe marudzi eLactococcus lactis bacteria. Iri muboka re lantibiotics, rinozivikanwa nechimiro chayo chakasiyana chine lanthionine uye methyllanthionine amino acids. Nisin inoratidza simba rekurwisa utachiona kurwisa mabhakitiriya akawanda ane gram-positive, kusanganisira hutachiona hwechikafu hwakadai seListeria monocytogenes naStaphylococcus aureus. Nekuda kwekugadzikana kwayo pakupisa uye kuenderana nemamiriro akasiyana-siyana ekugadzira chikafu, nisin inoshandiswa zvakanyanya semushonga wekuchengetedza hutachiona muchikafu kudzivirira kukura kwebhakitiriya uye kuwedzera hupenyu hwezvigadzirwa zvinoora.
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Oxytetracycline dihydrate CAS:6153-64-6
Oxytetracycline dihydrate imhando yeoxytetracycline, mushonga unorwisa mabhakitiriya uri muboka retetracycline. Kufanana nedzimwe tetracyclines, inodzivirira kugadzirwa kwemapuroteni emabhakitiriya nekusunga ku30S ribosomal subunit, nokudaro ichiita kuti pave nemigumisiro yebhakitiriya pakurwisa mabhakitiriya akasiyana-siyana egram-positive negram-negative. Oxytetracycline dihydrate yakafanana neoxytetracycline asi ine mamorekuru maviri emvura muchimiro chayo chekristaro. Inowanikwa mumhando dzakasiyana dzemishonga dzekushandiswa nevanhu nemhuka.
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Ornidazole CAS:16773-42-5
Ornidazole mushonga wekugadzira we nitroimidazole antibiotic uye antiprotozoal une simba guru rekurwisa mabhakitiriya asina aerobic neprotozoa. Unoshanda nekukuvadza DNA yehutachiona hwehutachiona, zvichikonzera kufa kwavo. Ornidazole inowanikwa mumishonga inonwiwa, kusanganisira mapiritsi ne suspensions, yekurapa hutachiona hwakasiyana-siyana, hwakadai se bacterial vaginosis, trichomoniasis, giardiasis, uye amoebiasis. Unowanzo pihwa mushonga nekuda kwekushanda kwayo, kushivirira, uye nzira iri nyore yekurapa.
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Oxacillin sodium munyu monohydrate CAS:7240-38-2
Oxacillin sodium salt monohydrate mushonga unorwisa mabhakitiriya une spectrum yakamanikana beta-lactam, wakafanana neoxacillin sodium salt, nekuwedzera imwe mvura muchimiro chayo chekristaro. Yakafanana nemethicillin nenafcillin, inoshanda kurwisa staphylococci inogadzira penicillinase. Oxacillin sodium salt monohydrate inodzivirira kugadzirwa kwemadziro emasero ebhakitiriya nekuvhiringidza peptidoglycan cross-linking, zvichiita kuti pave nemhedzisiro inouraya zvipembenene zvinokanganisa hutachiona. Inowanikwa mumhando dzejekiseni yekupa mushonga wemutsinga kana wemutsinga, inowanzo shandiswa munzvimbo dzehutano pakurapa hutachiona hunokonzerwa neStaphylococcus aureus inogadzira penicillinase.
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Pefloxacin mesylate CAS:70458-95-6
Pefloxacin mesylate mushonga unorwisa mabhakitiriya we fluoroquinolone une simba rekurwisa mabhakitiriya akawanda mukurwisa mabhakitiriya e gram-positive ne gram-negative. Unoshanda nekudzivisa kugadzirwa kweDNA yebhakitiriya kuburikidza nekubatana kwayo nema enzymes akaita seDNA gyrase ne topoisomerase IV, zvichiita kuti pave nemigumisiro yekuuraya mabhakitiriya. Pefloxacin mesylate inowanikwa mumishonga yakasiyana-siyana yemuromo uye jekiseni, ichipa nzira dzinoshanda dzekurapa hutachiona hwakasiyana-siyana.
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Novobiocin sodium munyu CAS:1476-53-5
Novobiocin sodium salt mushonga unorwisa mabhakitiriya unobva kuhutachiona uri wemhuri yecoumarin, pakutanga wakabviswa kubva kuStreptomyces strains. Une basa rekurwisa mabhakitiriya akawanda, kunyanya mabhakitiriya ane gram-positive, nekudzivisa DNA gyrase, enzyme inokosha inobatanidzwa mukudzokororwa kweDNA uye kunyorwa kwayo. Novobiocin inowanzo shandiswa mumarabhoritari e microbiology nekuda kwekudzivirira kwayo Staphylococcus aureus nedzimwe staphylococci dzine coagulase-positive, zvichiita kuti ive chishandiso chakakosha chekuziva mabhakitiriya uye kuyedza hutachiona.
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Nitrocefin CAS:41906-86-9
Nitrocefin imhando ye cephalosporin inoshandiswa mu microbiology kuona mashandiro e beta-lactamase mumabhakitiriya. Inoshanda senzira yekuongorora mabhakitiriya anogadzira ma enzymes e beta-lactamase anokwanisa hydrolyze beta-lactam antibiotics, akadai se penicillins ne cephalosporins. Nitrocefin inochinja ruvara kubva kuyero kuenda kutsvuku kana paine beta-lactamase, zvichibvumira kuona nekukurumidza mashandiro ema enzyme. Izvi zvinoita kuti nitrocefin ive chishandiso chakakosha mumakiriniki ekuongorora mabhakitiriya akapatsanurwa uye kutungamira sarudzo dzekurapa ma antibiotic.
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Oleandomycin phosphate CAS:7060-74-4
Oleandomycin phosphate mushonga unorwisa mabhakitiriya unobva kuStreptomyces antibioticus, unozivikanwa nekushanda kwawo nehutachiona hwakasiyana-siyana kurwisa mabhakitiriya ane gram-positive. Unodzivirira kugadzirwa kwemapuroteni emabhakitiriya nekusunga ku50S ribosomal subunit, zvichikonzera mhedzisiro yebhakitiriya. Oleandomycin phosphate inowanzoshandiswa mukurapa hutachiona hwemabhakitiriya muzvipfuyo nehuku. Inowanikwa mumhando dzakakodzera kunwiwa nemuromo kugadzirisa hutachiona hwekufema, matambudziko emudumbu, nezvimwe zvirwere zvebhakitiriya zvinokanganisa mhuka.
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Natamycin (Pimaricin) CAS:7681-93-8
Natamycin, inozivikanwawo sepimaricin, mushonga wefungus unowanikwa muchisikigo unogadzirwa nebhakitiriya reStreptomyces natalensis. Unoshandiswa zvakanyanya semushonga wekuchengetedza chikafu kudzivirira kukura kwefungus nembiriso muzvigadzirwa zvakasiyana-siyana zvemukaka, nyama, nezvinhu zvakabikwa. Natamycin inoshanda pakurwisa fungus dzakasiyana-siyana, dzinosanganisira Aspergillus, Penicillium, neFusarium, ukuwo isina njodzi yekudyiwa nevanhu. Chigadzirwa ichi chinozivikanwa nekugadzikana kwacho, kuramba kupisa, uye kusakanganisa zvakanyanya hunhu hwechikafu, zvichiita kuti chive sarudzo inofarirwa mukugadzira nekuchengetedza chikafu.
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Nadifloxacin CAS:124858-35-1
Nadifloxacin mushonga unorwisa mabhakitiriya unoshandiswa pakurapa hutachiona hweganda hwakasiyana-siyana. Une simba guru rekuuraya mabhakitiriya pakurwisa mabhakitiriya akasiyana-siyana, kunyanya ayo anobatanidzwa mukuputika kweganda uye dermatitis. Nadifloxacin inoshanda nekudzivisa kudzokororwa kweDNA remabhakitiriya, nokudaro ichibvisa mabhakitiriya ane njodzi pamusoro peganda. Mushonga uyu unowanikwa muchimiro chemakirimu, majeli, kana mafuta ekushandisa kunze. Unobvumirwa zvakanaka uye unowanzo nyorerwa nenyanzvi dzehutano nekuda kwekushanda kwawo uye kuchengetedzeka kwawo pazvirwere zveganda.
