Fmoc-D-Cys(Trt)-OH CAS:167015-11-4

Fmoc-D-Cys(Trt)-OH inoshanda senzira yekutanga mukugadzirwa kwepeptide, kunyanya mukugadzira mapeptide ane D-enantiomer yecysteine ​​nemazvo. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa kuti pane zvinoitwa panguva yekubatanidza peptide, nepo boka retrityl richiwedzera dziviriro yakawedzerwa kuboka rethiol. Vaongorori vanoshandisa zvakanyanya Fmoc-D-Cys(Trt)-OH mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga yepeptide-based therapeutics, biomaterials, uye mapeptide ane structural motifs chaiwo. Kuenderana kwayo nemaitiro ekugadzira peptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweD-cysteine ​​​​mu peptide sequences, zvichiwedzera chiyero che synthesizable peptides. Uyezve, Fmoc-D-Cys(Trt)-OH inowana rubatsiro muzvidzidzo zvine chekuita ne protein engineering, disulfide bond formation, uye peptide conjugation reactions. Kushandiswa kweboka rekudzivirira retrityl kunogonesa kushandiswa kwakanyatsojeka kwekuita kweD-cysteine, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-D-Cys(Trt)-OH inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa kuita kweD-cysteine ​​kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane iyi amino acid inokosha muD-configuration.