Geneticin disulfate (G418 sulfate) CAS:108321-42-2

Geneticin disulfate, inozivikanwawo seG418 sulfate, mushonga unorwisa mabhakitiriya une simba unobva kuMicromonospora rhodorangea. Uri muboka remishonga inorwisa mabhakitiriya yeaminoglycoside uye unoshandiswa zvakanyanya mukutsvagisa kwebiology yemamorekuru sechinhu chinosarudza masisitimu ekukura kwemasero. Geneticin disulfate inodzivirira kugadzirwa kwemapuroteni mumasero eprokaryotic ne eukaryotic nekusunga ku ribosome, zvichiita kuti ive yakakosha pakusarudza masero akagadziriswa majini anoratidza majini ekudzivirira.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro:

Munzvimbo dzerabhoritari, geneticin disulfate (G418 sulfate) inowanzo shandiswa mukuyedza masero ekudzivirira masero kusarudza nekuchengetedza mitsetse yemasero ine mavector ekuratidza ane majini ekudzivirira, akadai se neomycin phosphotransferase. Masero aya anogona kurarama kana paine geneticin disulfate nekuda kwekuratidzwa kwejini rekudzivirira, zvichibvumira vaongorori kuparadzanisa nekudzidza huwandu hwemasero akagadziriswa majini. Vaongorori vanoshandisa geneticin disulfate mumashandisirwo akasiyana-siyana, kusanganisira kugadzira masero akagadzikana, matekiniki ekugadzirisa majini seCRISPR-Cas9, uye kugadzirwa kwemapuroteni akasanganiswa. Nekuisa geneticin disulfate muchimiro chekurima, huwandu hwemasero chaiwo hunogona kupfumiswa kana kuparadzaniswa zvichienderana nekukwanisa kwavo kurarama kusarudzwa kwemishonga inorwisa mabhakitiriya. Kugadzirisa huwandu uye nguva yekurapa geneticin disulfate kwakakosha kuti uwane kumanikidzwa kwakasarudzwa uku uchideredza cytotoxicity uye mhedzisiro isiriyo pamasero asina kubatwa nechirwere. Kunyatso tarisa kugara kwemasero, hunhu hwekukura, uye maitiro ekutaura majini kunobatsira kuona mhedzisiro yekuedza inobudirira pakushandisa geneticin disulfate muzvidzidzo zvekurima masero. Vaongorori vanofanirwa kutevedzera mitemo yakagadzwa yekushandiswa kwe geneticin disulfate, kusanganisira nzira dzakakodzera dzekuyedza, kubata, uye kurasa, kuchengetedza mitemo yekuchengetedza marabhoritari uye kukurudzira mhedzisiro yesainzi chaiyo. Kushanda pamwe chete pakati pevasayendisiti, vashandi vemumarabhoritari, nevatungamiriri vemitemo kunotsigira kushandiswa kwe geneticin disulfate zvine mutoro uye zvinobudirira mukutsvagisa kwe molecular biology, zvichisimudzira kunzwisisa kwedu maitiro emasero uye matekiniki ekugadzirisa majini.

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Mamwe Mashoko:

Kuumbwa	C20H42N4O14S
Kuyedza	99%
Chitarisiko	upfu chena
Nhamba yeCAS	108321-42-2
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.