Letrozole CAS:112809-51-5 Manufacturer Supplier Featured Image

Letrozole CAS:112809-51-5 Mugadziri Mutengesi

Letrozole chikamu chechizvarwa chitsva che aromatase inhibitors anosarudza zvakanyanya uye inogadzirwa nemhando yebenzotriazole derivative.Letrozole inhibits aromatase kudzikisa estrogen mazinga, nokudaro kudzivirira estrogen kubva mukukurudzira bundu kukura.Yayo mu vivo chiitiko ndeye 150-250 nguva yakasimba kupfuura yechizvarwa chekutanga aromatase inhibitor Amarante.Sezvo yakanyanya kusarudzwa, haizokanganisa glucocorticoid, mineralocorticoid uye thyroid mabasa;kunyangwe pamadosi akakwirira, haizove nechero inhibiting mhedzisiro pane adrenal corticosteroid secretion, ichipa iyo yakanyanya kurapwa index.

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Application uye Effect

Letrazole inogona kugadzirwa mumatanho maviri kubva ku4- bromomethyl-benzonitrile ine 1,2,4-triazole uye ichizvarwa chechitatu aromatase inhibitor.Iyo yakanyanya kujeka inhibitor yeP450arom iyo inodzivirira kushandurwa kwe androstenedione kuita estrone.Kuderedzwa kwe plasma estrogen kwaive nekukurumidza uye kwenguva refu.Izvi zvinopedzwa pasina inhibition yeimwe steroid biosynthesis ichiita iyo inonyanya kusarudzwa aromatase inhibitor yakaedzwa.Letrazole ine inoshamisa antitumor basa, inoshivirirwa zvakanaka uye haina chepfu mhedzisiro.Iine simba rakapetwa ka10,000 kupfuura aminoglutethimide, in vivo, yekutanga yakasimbiswa aromatase inhibitor.

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Composition	C17H11N5
Assay	99%
Chitarisiko	Upfu chena
CAS Nha.	112809-51-5
Packing	25KG
Sherufu Hupenyu	2 years
Storage	Chengetedza munzvimbo inotonhorera uye yakaoma
Certification	ISO.