Letrozole CAS:112809-51-5 Mugadziri Mutengesi Mufananidzo Wakaratidzwa

Letrozole CAS:112809-51-5 Mugadziri weLetrozole

Letrozole chikamu chechizvarwa chitsva chemishonga inodzivirira aromatase zvakanyanya uye imishonga inogadzirwa nebenzotriazole yakagadzirwa. Letrozole inodzivirira aromatase kuderedza mazinga eestrogen, nokudaro ichidzivirira estrogen kuti isakurudzire kukura kwegomarara. Basa rayo mumuviri rine simba rakapetwa ka150-250 kupfuura remushonga unodzivirira aromatase wechizvarwa chekutanga Amarante. Sezvo ichisarudza zvakanyanya, haizokanganisi glucocorticoid, mineralocorticoid uye thyroid; kunyangwe kana ikashandiswa zvakanyanya, haizove nemhedzisiro inodzivisa kuburitswa kwecorticosteroid muadrenal, zvichiipa chiyero chepamusoro chekurapa.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Letrazole inogona kugadzirwa mumatanho maviri kubva pa4- bromomethyl-benzonitrile ne1,2,4-triazole uye inodzivirira aromatase yechizvarwa chechitatu. Inodzivirira zvakanyanya P450arom iyo inodzivirira kushandurwa kwe androstenedione kuita estrone. Kuderedzwa kwe estrogen muplasma kwakaitika nekukurumidza uye kwenguva refu. Izvi zvinoitwa pasina kudziviswa kwemamwe ma steroid biosynthesis zvichiita kuti ive inhibitor ye aromatase inosarudza zvakanyanya yakaedzwa. Letrazole ine basa rinoshamisa rekudzivirira bundu, inoshivirira zvakanaka uye haina migumisiro ine chepfu. Ine simba rakapetwa ka10,000 kupfuura aminoglutethimide, in vivo, iyo yekutanga aromatase inhibitor yakasimbiswa zvakanaka.

Muenzaniso weChigadzirwa

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C17H11N5
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	112809-51-5
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.