Levofloxacincarboxylicacid CAS:100986-89-8

Levofloxacin carboxylic acid, sechikamu che levofloxacin, inobatanidzwa mumabasa akasiyana-siyana emishonga. Inoratidza hunhu hwemabhakitiriya uye inobatsira mumhedzisiro yekurapa inobatanidzwa nekushandiswa kwe levofloxacin. Mumamiriro ekurapa, kudzidza nekuongorora levofloxacin carboxylic acid kwakakosha pakunzwisisa pharmacokinetics uye pharmacodynamics ye levofloxacin, mushonga unorwisa mabhakitiriya unoshandiswa kurapa hutachiona munzvimbo dzakasiyana-siyana dzemuviri. Levofloxacin carboxylic acid inobatanidzwa mukubviswa kwe levofloxacin mumuviri, zvichikanganisa kushanda kwayo uye kuchengetedzeka kwayo. Uyezve, kuzivikanwa uye kuverengwa kwe levofloxacin carboxylic acid mumienzaniso yebhayoloji kwakakosha pakudzidza kwe pharmacokinetic, zvichipa ruzivo rwe metabolism yemishonga, kubviswa kwayo, uye kudyidzana kunogona kuitika. Ruzivo urwu runobatsira mukuvandudza nzira dzekuyedza uye kuona kushanda kwekurapa uku uchideredza njodzi yemigumisiro yakaipa inobatanidzwa ne levofloxacin therapy. Uyezve, kuedza kutsvagisa kwakatarisana nebasa relevofloxacin carboxylic acid mukushanda kweantibacterial uye nzira dzekudzivirira chirwere kwakakosha pakunzwisisa zvazvinoreva pakurapa levofloxacin. Zvidzidzo zvinoongorora kukanganisa kwayo pahutachiona hwebhakitiriya uye maitiro avo ku levofloxacin zvinopa ruzivo rwakakosha rwekuvandudza nzira dzekurapa uye kurwisa kuramba kwemishonga inorwisa mabhakitiriya. Mukupfupisa, levofloxacin carboxylic acid ine basa guru mukushandiswa kwemishonga uye mukiriniki kwelevofloxacin. Mupiro wayo mukushandiswa kwemishonga, pharmacokinetics, basa rekurwisa mabhakitiriya, uye nzira dzekudzivirira chirwere zvinosimbisa kukosha kwayo mukutsigira kurapwa kwemishonga inorwisa mabhakitiriya kunoshanda uye kwakachengeteka. Sechikamu chemamiriro akafara emishonga inorwisa mabhakitiriya, levofloxacin nemetabolites yayo, kusanganisira levofloxacin carboxylic acid, inoramba iri chinhu chikuru chekutsvaga uye kuferefeta kwekiriniki kwakanangana nekugadzirisa hutachiona hwebhakitiriya uye kufambira mberi kwekutarisira varwere.