Mirabegron CAS:223673-61-8 Manufacturer Supplier Featured Image

Mirabegron CAS:223673-61-8 Mugadziri Wekutengesa

Mirabegron ndeyekurapa kwekukurumidzira, urinary frequency, uye urinary urge urinary incontinence yakabatana neakawandisa bladder (OAB).Mirabegron inogadzirwa nekubatanidza 4-nitrophenethyl amine kune (R) -2-hydroxy-2-phenylacetic acid.Iyo amide inoguma inoderedzwa kuita amine.Boka re nitro rinobva raderedzwa uye mhedzisiro yacho inobatanidzwa ku 2-(2-aminothiazol-4-yl) acetic acid kuti ipe mirabegron.

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Mirabegron is an orally active β3-adrenoceptor agonist parizvino irikuitwa neAstellas Pharma yekurapa dundira (OAB).Mushonga ndeye nanomolar EC50 antagonist inopesana nevanhu β3-AR biochemical assays ine yakanaka selectivity pamusoro pe b1- uye β2-ARs.Mirabegron inoratidza nzira itsva nekunangidzira iyo β3-AR yekuzorodza dundira kubatsira kubata OAB zviratidzo zvakadai sekuwedzera weti yekukurumidzira uye kuwanda uye nekukasira incontinence.Zvisinei, mirabegron inonzi cytochrome P450 2D6 inhibitor, uye inomutsa kushushikana kwekubatana kwezvinodhaka-zvinodhaka pamwe chete nekutonga kweimwe cytochrome P450 2D6 substrates.

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Composition	C21H24N4O2S
Assay	99%
Chitarisiko	Ichena kusvika Pale Yellow powder
CAS Nha.	223673-61-8
Packing	25KG
Sherufu Hupenyu	2 years
Storage	Chengetedza munzvimbo inotonhorera uye yakaoma
Certification	ISO.