Mirabegron CAS:223673-61-8 Mugadziri weMugadziri Mufananidzo Wakaratidzwa

Mirabegron CAS:223673-61-8 Mugadziri wezvigadzirwa

Mirabegron inoitirwa kurapa kushaikwa kwemvura, kuwanda kweweti, uye kusakwanisa kudzora weti kunokonzerwa nekushandisa dundira zvakanyanya (OAB). Mirabegron inogadzirwa nekubatanidza 4-nitrophenethyl amine ku (R)-2-hydroxy-2-phenylacetic acid. Amide inobuda inoderedzwa kuita amine. Boka re nitro rinoderedzwa uye rinobuda rinosanganiswa ne 2-(2-aminothiazol-4-yl) acetic acid kuti ripe mirabegron.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Mirabegron mushonga unoshanda nemuromo weβ3-adrenoceptor agonist uri kugadzirwa neAstellas Pharma wekurapa dundira rinoita basa zvakanyanya (OAB). Mushonga uyu unopesana neEC50 nanomolar kurwisa bvunzo dze β3-AR dzemunhu dzine sarudzo yakanaka pamusoro pe b1- ne β2-ARs. Mirabegron inoratidza nzira itsva nekutarisa β3-AR yekuzorodza dundira kuti ibatsire kudzora zviratidzo zveOAB zvakaita sekuwedzera kwekukurumidzira kweweti uye kuwanda kwekusagona kudzora weti. Zvisinei, mirabegron mushonga unodzivirira cytochrome P450 2D6, uye unokonzera kunetseka kwekubatana kwemishonga nezvinodhaka pamwe chete nekushandiswa kwezvimwe zvinhu zve cytochrome P450 2D6 panguva imwe chete.

Muenzaniso weChigadzirwa

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C21H24N4O2S
Kuyedza	99%
Chitarisiko	Upfu hwejena kusvika hweyero isina kujeka
Nhamba yeCAS	223673-61-8
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.