N-oleoylethanolamine CAS:111-58-0

N-oleoylethanolamine (OEA) ine mhedzisiro dzakasiyana-siyana dzezvipenyu uye inobatanidzwa mumabasa akasiyana-siyana emuviri. Mundima yekudzora chishuwo chekudya uye kudzora uremu, OEA inoita basa rakakosha sechinhu chinogutsa. Pakudya mafuta ekudya, huwandu hweOEA hunowedzera uye hunoratidza uropi kuti hunzwe kuguta uye kuderedza kudya, nokudaro zvichibatsira mukudzora kuenzana kwesimba nehuremu hwemuviri. Hunhu uhwu hweOEA hwakatungamira mukutsvagurudza kugona kwayo semushonga wechisikigo wekudzvinyirira chishuwo uye chinangwa chehurongwa hwekugadzirisa kufuta. Uyezve, OEA yakaongororwa nekuda kwekubatanidzwa kwayo mu metabolism yemafuta uye energy homeostasis. Yakaratidzwa kuti inochinja kuunganidzwa kwemafuta uye inokanganisa thermogenesis, inogona kukanganisa maitiro e metabolism ane chekuita nekufutisa, chirwere cheshuga, uye hutano hwemwoyo. Nekuda kweizvozvo, OEA iri kuferefetwa nekuda kwekugona kwayo kurapa mukugadzirisa matambudziko e metabolism nekutsigira hutano hwe metabolism. Kuwedzera kune mabasa ayo mu appetite ne metabolism, OEA inoratidza hunhu hwekudzivirira tsinga uye yakaongororwa nekuda kwekukanganisa kwayo pamanzwiro, kupindura kwekushushikana, uye kushanda kwepfungwa. Tsvagiridzo inoratidza kuti OEA inogona kudzivirira tsinga dzemuviri uye kubatsira mukugara zvakanaka kwepfungwa uye kugadzirisa kushushikana, zvichiratidza kukosha kwayo muhutano hwepfungwa uye tsvagiridzo yetsinga. Uyezve, kudyidzana kweOEA ne endocannabinoid system nedzimwe nzira dzekutumira zviratidzo kwakakurudzira kuongororwa kwekugona kwayo mukuchinja kwemarwadzo nekuzvimba. Kugona kwayo kukanganisa maonero ekurwadziwa uye maitiro ekuzvimba kunoiisa sechinhu chinonakidza mukugadzirwa kwenzira itsva dzekurapa marwadzo nekudzivirira kuzvimba. Kazhinji, N-oleoylethanolamine (OEA) inoratidza mabasa akasiyana-siyana ezvebhayoloji akakonzera kutsvagurudza kwakakura mukushandiswa kwayo kwekurapa. Kubva pakubatanidzwa kwayo mukutonga kwekudya uye metabolism yemafuta kusvika pahunhu hwayo hwekudzivirira tsinga nekudzivirira kuzvimba, mabasa eOEA ane mativi akawanda anoita kuti ive chinangwa chinokwezva chekuvandudza nzira dzekurapa dzine chekuita nekufutisa, matambudziko emetabolism, hutano hwetsinga, uye kugadzirisa marwadzo.