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N-Acetyl-D-Glucosamine CAS: 7512-17-6 Mugadziri weMugadziri
N-Acetyl-D-Glucosamine iN-acetyl derivative yeglucosamine. Mumakemikari iamide iri pakati peglucosamine neacetic acid. Chikamu chimwe chete cheN-acetlyglucosamine chakabatana ne serine kana threonine residues pamapuroteni enuclear ne cytoplasmic -O-GlcNAc, ipuroteni inoshandurwa inoonekwa nguva dzose mushure mekushandurwa. Mapuroteni akagadziriswa eO-GlcNAc anobatanidzwa mukuona mamiriro ekudya kwenzvimbo yakatenderedza masero uye kugadzirisa mashandiro emapuroteni emasero zvinoenderana. O-GlcNAc inodzora mhinduro dzemasero kumahormone akadai se insulin, inotanga mhinduro yekudzivirira kushushikana, inogadzirisa kugona kwesero kukura nekupatsanura, uye inodzora kunyorwa kwemajini. Muvanhu, inowanikwa muganda, cartilage uye mutsinga yeropa sechikamu che hyaluronic acid, uye mapfupa, cornea uye aorta sechikamu che keratan sulfate.
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Creatine Pyruvate CAS: 55965-97-4 Mugadziri Mutengesi
Creatine Pyruvate imushonga une Creatine ne pyruvic acid uye unoshandiswa nevanogadzira muviri semushonga wekuwedzera simba remuviri uye unonyungudika zvachose mumvura. Mumushonga wayo wekuwedzera, Creatine Pyruvate inonyungudika kagumi kupfuura muchimiro chayo chega chega. Zvidzidzo zvekiriniki zvakaratidza kuti Pyruvate inoderedza mafuta emuviri pasina kukanganisa mapuroteni emhasuru, chinhu chakakosha mukuwana tsandanyama dzisina mafuta akawanda. Creatine Pyruvate supplements itsigiro yakanaka yezvekudya kune vatambi vari kutsvaga kuwedzera kushanda kwetsandanyama uye kutsungirira muzvirongwa zvekurovedza muviri zvine simba.
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Vhitamini A Palmitat CAS:79-81-2 Mugadziri Mutengesi
Retinyl palmitate iri muboka remakemikari anonzi retinoids, ayo akafanana nevhitamini A. Inobatsira pakuona, ganda uye mashandiro ekudzivirira muviri, inodzivirira kuwanda kwemasero uye inodzivirira kenza. Inhengo inokosha yekudya pamwe nekurapa. All-trans-retinyl palmitate i-all-trans-retinyl ester inowanikwa nekubatanidzwa kweboka recarboxy repalmitic (hexadecanoic acid) neboka rehydroxy re all-trans-retinol. Inoshandiswa muzvigadzirwa zvekushongedza kurapa zvirwere zvakasiyana-siyana zveganda zvakaita semapundu, kukwegura kweganda, makwinya, matema, uye zvakare kudzivirira kubva kupsoriasis. Ine basa seEscherichia coli metabolite, human xenobiotic metabolite uye antioxidant. I retinyl palmitate uye all-trans-retinyl ester. Inoshanda zvine chekuita ne all-trans-retinol.
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Benfotiamine CAS:22457-89-2 Mugadziri wezvigadzirwa
S-Benzoylthiamine O-monophosphate (Benfotiamine) chinhu chinobva kuS-acyl thiamine chinobva ku amphiphilic. Ivhitamini inonyungudika mumafuta. Benfotiamine ine ring yethiazole. Benfotiamine ine bioavailability yakakura kupfuura thiamine.
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Collagen Hydrolyzed CAS:92113-31-0 Mugadziri Mutengesi
Kolajeni yakasanganiswa inonziwo kolajeni yakasanganiswa. Kolajeni yakasanganiswa imhando itsva yechigadzirwa chekolajeni, inogadzirwa kubva kucollagen kana kuti collagen-rich-rich. Pamusoro pekuumbwa kweamino acid yekolajeni (inenge 30% yeamino acid residues yese iglycine), inewo 15-30% yemaamino acid maviri asingawanzo kuwanikwa mune mamwe mapuroteni, proline ne4-hydroxyproline Kuwedzera kune acid), inewo hunhu hwehuremu hudiki hwemamorekuru, uye kuumbwa kwayo kunonyanya kuumbwa nemapeptide madiki ane huremu hwemamorekuru husingasviki 3000.
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Vitamin E yechisikigo CAS: 59-02-9 Mugadziri weVatengesi
Vitamin E Oil ivhitamini inonyungudika mumafuta, inozivikanwawo setocopherol. Ndiyo imwe yeantioxidants inonyanya kukosha. Izvinhu zvinonyungudika mumafuta zvakaita seethanol, uye hazvinyungudike mumvura, kupisa, acid stable, base-labile. Inonzwa oxygen asi hainzwe kupisa. Uye basa revhitamini E rakaderera zvakanyanya pakukangwa.α-Tocopherol inogadzirwa kubva kuγ-tocopherol nekushanda kweenzyme γ-tocopherol methyltransferase. Ndiyo mhando huru yeVitamin E muplasma yevanhu. Inowanikwa mumafuta embeu yezuva.
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Curcumin (turmeric) 95% CAS:458-37-7 Mugadziri wezvinhu
Curcumin ndiyo pigment huru yeyero mu turmeric ne curry uye ine mabasa e antioxidant, anti-inflammatory, uye antibumor. Inodzivirira kugadzirwa kwe nitric oxide (NO) (IC50 = 6 μM) uye inoderedza inducible nitric oxide synthase (iNOS) mumasero e RAW 264.7 anosimudzirwa neLPS. Curcumin inodzivirira kuburitswa kwe histamine uye inflammatory cytokines TNF-α, IL-1β, IL-6, uye IL-8 kubva kumasero e HMC-1 mast. Mumuviri, curcumin inoderedza huwandu hwe histamine ne TNF-α muropa, inodzivirira kuchinja kwe histopathological mumhino mudumbu, uye inoderedza huwandu hwekutsvedza uye kukwesha mhino mumuenzaniso wembeva we ovalbumin-induced rhinitis.
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Vhitamini B1 (Thiamine Hydrochloride) CAS:67-03-8 Mugadziri weMugadziri
Thiamine Hydrochloride imhando yemunyu we thiamine (vhitamini B1), vhitamini inokosha pakugadzirwa kwemuviri, kukura kwemasero, kutapurirana kwetsinga uye kugadzirwa kweacetylcholine. Vhitamini B1 inobatsira kudzivirira matambudziko akasiyana-siyana ehutano anosanganisira kukuvara kwemoyo.
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Hydroxycobalamin HCL CAS:78091-12-0 Mugadziri wezvinhu
Hydroxycobalamin (ohcbl, kana B12a) imhando yechisikigo yevhitamini B12, kana imwe yemhando dzevhitamini B12. Inhengo huru yeboka recobalamine. Mabhakitiriya mazhinji anogadzira mavhitamini anogadzira vhitamini B12 mukutengeserana muchimiro chehydroxycobalamin. Hydroxycobalamin itsvuku yakasviba. Vhitamini B12 mumuviri wemunhu haiwanzo kuwanikwa muchimiro chehydroxycobalamin. Zvisinei, muvanhu, hydroxycobalamin inoshandurwa nyore nyore kuita coenzyme inobatsira yevhitamini B12. Mushonga wehydroxycobalamin ijekiseni rayo risina utachiona, rinoshandiswa kurapa kushomeka kwevhitamini uye chepfu yecyanide (nekuti inoenderana nemaion ecyanide).
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Collagen II CAS:9064-67-9 Mugadziri Mutengesi
Collagen ndiyo inonyanya kukosha mu extracellular matrix ine mapuroteni akawanda e fibrous structural muzvikamu zvepamusoro. Inowanikwa zvakanyanya mu fibrous tishu dzakadai seganda, ligament ne tendon muchimiro che fibrils refu uye inowanikwawo mu cornea, mitsipa yeropa, mapfupa, cartilage, intervertebral disc nemudumbu. Aya ndiwo mapuroteni akawanda mumhuka dzinoyamwisa anoumba anopfuura 30% yemapuroteni ese ari mumuviri wemhuka.
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Nicotinamide Riboside (Chloride) CAS:23111-00-4 Mugadziri weMugadziri
Nicotinamide Riboside Chloride ndiyo chloride salt form ye nicotinamide riboside (NR).NR imhando itsva ye pyridine-nucleoside yevhitamini B3 inoshanda senzira yekutanga nicotinamide adenine dinucleotide (NAD) kana NAD+. Nicotinamide riboside chloride imhando yekristaro yeNicotinamide riboside (NR) chloride. Nicotinamide riboside chloride inowedzera mazinga eNAD[+] uye inoita kuti SIRT1 neSIRT3 zvishande, zvichiguma nekuwedzera oxidative metabolism uye kudzivirira kubva kumafuta akawanda anokonzerwa nekudya. Nicotinamide riboside chloride inoshandiswa muzvikafu zvinovaka muviri.
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D-Fructose 1,6-Disphosphate Trisodium Munyu CAS:38099-82-0
Fructose-1,6-biphosphate (F1,6P) imhando yeglycolytic inogadzirwa nekutamiswa kwephosphate kubva kuATP kuenda kufructose-6-phosphate neenzyme phosphofructokinase. Fructose-1,6-biphosphate, pamwe chete nefructose-2,6-biphosphate, inogadzirisa mashandiro ephosphofructokinase-1 (PFK-1), danho rinoganhurira muglycolysis. Munguva yeglycolysis, aldolase inoparadzanisa Fructose-1,6-biphosphate kuita dihydroxacetone phosphate (DHAP) uye glyceraldehyde phosphate. Fructose-1,6-biphosphate zvakare inyanzvi ye allosteric activator yeM2 isoform yePyruvate Kinase (PK-M2), iyo inonyanya kushandiswa mumasero ekenza.
