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N,N-Bis(2-hydroxyethyl) -2-aminoethanesulfonic acid sodium munyu CAS:66992-27-6
N,N-Bis(2-hydroxyethyl) -2-aminoethanesulfonic acid sodium munyu, inozivikanwawo seHEPES sodium munyu, ikemikari inosanganiswa inowanzoshandiswa se pH buffering agent mubiological and chemical laboratories.Inobatsira kuchengetedza yakagadzikana pH renji, ichiita kuti ive yakakodzera kune mashandisirwo akadai sesero tsika, enzyme assays, zvidzidzo zveprotein, electrophoresis, uye kugadzirwa kwemishonga.HEPES sodium munyu inovimbisa mamiriro akakwana ezvipenyu uye inosimudzira huchokwadi uye kuvimbika kwemhedzisiro yekuedza.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
2'- (4-Methylumbliferyl) -alpha-DN-acetylneuraminic acid sodium munyu ikemikari inowanzoshandiswa mukuongorora uye tsvakurudzo yekuongorora.Iyo iine fluorescent yakanyorwa kubva kune sialic acid, rudzi rwemakhahydrates molecule inowanikwa pamusoro pemasero.
Mushonga uyu unoshandiswa se substrate ye enzymes inonzi neuraminidases, iyo inoshanda kubvisa sialic acid masara kubva glycoproteins uye glycolipids.Kana ma enzymes aya achiita pa 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium munyu, inobudisa chigadzirwa chefluorescent chinonzi 4-methylumbelliferon.
Iyo fluorescence inogadzirwa nekomboni inogona kuyerwa uye kuverengerwa, ichipa ruzivo nezvebasa reneuraminidase enzymes.Izvi zvinonyanya kubatsira mukudzidza kwezvirwere zvakasiyana-siyana uye mamiriro ane chekuita neaberrant sialic acid metabolism.
Mushonga wacho unoshandiswawo pakuongorora zvirwere, zvakadai sekuona utachiona hunobatanidza neuraminidase.Muzviyero izvi, musanganiswa unoshandiswa kuona kuvepo kwehutachiwana chaihwo kana kuongorora kushanda kweneuraminidase inhibitors mumishonga inorwisa mavhairasi.
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TAPSO CAS:68399-81-5 Mutengo wemugadziri
TAPSO (3--[N-tris(hydroxymethyl)methyl]amino] -2-hydroxypropanesulfonic acid) izwitterionic buffer inowanzoshandiswa mukutsvakurudza kwebiological uye biochemical.Iyo inonyatso bhafa mumiririri ine pKa padyo nepH yemuviri, ichiita kuti ive yakakodzera kuchengetedza yakagadzikana pH muzviyedzo zvebiology.TAPSO inowanzo shandiswa mukunatswa kweprotein, enzyme assays, cell tsika, uye electrophoresis application.Kunyungudika kwayo kwepamusoro kwemvura uye kukanganiswa kwakaderera kwemaitiro ehupenyu kunoita kuti ive sarudzo yakakurumbira munharaunda yesainzi.TAPSO inozivikanwa nekushomeka kwayo pakuita enzyme uye inowanzo shandiswa seimwe nzira kune mamwe ma-buffering agents seTris kana phosphate buffers.
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N-Acetyl-L-cysteine CAS:616-91-1
N-Acetyl-L-cysteine (NAC) imhando yakagadziridzwa yeamino acid cysteine.Inopa sosi yecysteine uye inogona kushandurwa nyore nyore kuita tripeptide glutathione, ine simba antioxidant mumuviri.NAC inozivikanwa neayo antioxidant uye mucolytic zvivakwa, zvichiita kuti ibatsire mune dzakasiyana siyana hutano maapplication.
Se antioxidant, NAC inobatsira kuchengetedza maseru kubva mukukuvadzwa kunokonzerwa nemahara radicals, reactive oxygen marudzi, uye chepfu.Iyo zvakare inotsigira glutathione synthesis, iyo inoita basa rakakosha mukuita kwemuviri detoxification maitiro uye kuchengetedza ine hutano immune system.
NAC yakadzidzwa nezve mabhenefiti ayo muhutano hwekufema, kunyanya kune vanhu vane mamiriro akaita senge chronic bronchitis, COPD, uye cystic fibrosis.Inowanzoshandiswa se expectorant kubatsira mutete uye kusunungura mucus, zvichiita kuti zvive nyore kubvisa mhepo.
Uyezve, NAC yakaratidza chivimbiso mukutsigira hutano hwechiropa nekubatsira mukubviswa kwezvinhu zvine chepfu, senge acetaminophen, inogadzirisa marwadzo.Inogonawo kuva nemigumisiro yekudzivirira pakukuvara kwechiropa kunokonzerwa nekunwa doro.
Pamusoro peiyo antioxidant uye yekufema kutsigira zvivakwa, NAC yakaongororwa nekuda kwezvainogoneka muhutano hwepfungwa.Imwe tsvakurudzo inoratidza kuti inogona kuva nemigumisiro yakanaka pakusagadzikana kwepfungwa, zvakadai sekuora mwoyo uye obsessive-compulsive disorder (OCD).
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PIPES CAS:5625-37-6 Mutengo wemugadziri
PIPES (piperazine-1,4-bisethanesulfonic acid) is zwitterionic buffering compound inowanzoshandiswa mukutsvakurudza kwebiological uye biochemical.Iyo inoshanda pH buffer ine hunyanzvi hwekuchengetedza yakagadzikana pH mamiriro mupH ye6.1 kusvika 7.5.PIPES ine kukanganiswa kudiki nemabiomolecules uye inokodzera tembiricha-inotsamira assays.Inowanzoshandiswa mune gel electrophoresis maitiro uye kugadzirwa kwemishonga semugadziri wekugadzikana.Pakazere, PIPES inosiyana-siyana uye inoshandiswa zvakanyanya mumichina yekuedzwa kwakasiyana-siyana.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniumM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2', 6'-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester ikemikari yemakemikari ine maitiro akaoma emakemikari.Iine sulfopropylacridinium boka uye carboxylate ester inoshanda boka.Kuvapo kweiyo ester moiety kunoratidza kuti inoshanda uye inogona kushandiswa seyekunyora kana kugadzirisa agent ye biomolecules.
Boka remukomboni wesulfopropylacridinium rinoratidza kuti rinogona kunge riine mashandisiro mu fluorescence-based assays, kwarinogona kushandiswa sefluorescent probe kana dhayi yekuona uye kuongorora biomolecules.Inogona zvakare kuve nekukosha muzvidzidzo zvemaserura maitiro, senge intracellular calcium signing.
Kubatanidzwa kweboka reNHS ester kunoratidza kuti inogona kuita nemaminerari ekutanga, akadai seaya anowanikwa mumapuroteni kana peptide, kuti aite zvisungo zvakagadzikana zveamide.Uku kuita zvekare kunoita kuti ive yakakosha kune bioconjugation application, kwainogona kushandiswa kunyora kana kugadzirisa biomolecules nemamwe mamorekuru anoshanda, akadai se fluorophores kana tag.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide ikamu rinoshandiswa muzvidzidzo zvakasiyana-siyana zvebiochemical, kunyanya pakuona uye kuona kwekuita kwe enzyme.Iyo substrate inogona kuve hydrolyzed nema enzymes chaiwo, zvichikonzera kuburitswa kwechigadzirwa chine ruvara kana fluorescent.
Mushonga uyu unowanzoshandiswa mukuedza kuona kuvepo uye kuita kwema enzymes akadai beta-galactosidase uye beta-glucuronidase.Aya ma enzymes anotsemura mapoka eacetyl uye glucosaminide kubva kune substrate, zvichiita kuti paumbwe chromophore yebhuruu kana yegirini.
Chimiro chakasiyana che5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide inobvumira kuonekwa nyore uye quantification yebasa re enzyme.Kushandiswa kwayo mumhando dzakasiyana dzekuyedza, kusanganisira histochemistry, immunohistochemistry, uye cell-based assays, zvakabatsira mukunzwisisa kuri nani kwemabasa ee enzyme.
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Sodium Munyu munyu CAS:139-41-3 Mutengo wemugadziri
N,N-Bis(2-hydroxyethyl) glycine sodium munyu ikemikari inoshandiswa seyakavharisa mumhando dzakasiyana dzebiochemical uye biophysical application.Inobatsira kuchengetedza yakagadzikana pH nhanho mumamiriro ekuyedza, zvichiita kuti ishande muzvidzidzo zve enzyme, tsvakiridzo yeprotein, sero tsika, uye Western blotting matekiniki.
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Spinosad CAS:131929-60-7 Mugadziri Mutengesi
Spinosad iboka 5 nicotinic acetylcholine receptor agonist, iyo inokonzera kusagadzikana kwemhasuru kubvongodzwa uye kudedera kwechipiri kune motor neuron activation.Kugara kwenguva refu kunokonzera kuremara uye kufa kwenhata.Kufa kwenhata kunotanga mukati memaminitsi makumi matatu ekutora uye mumaawa mana kwapera.Spinosad haipindirani nenzvimbo dzinosungirirwa dzezvimwe zvipembenene (GABA-ergic kana nicotinic).
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Rotenone CAS:83-79-4 Mugadziri Mutengesi
Rotenone zvese dumbu uye yekubata chepfu yearthropods.Kukurumidza kugogodza kuita kunonzi kukadzikira kuwanikwa kwenicotinamide adenine dinucleotide kushanda secofactor munzira dzakasiyana siyana dzebiochemical dzinosanganisira kutenderera kweKrebs, nekudaro ichivharira mitochondrial kufema ma enzymes.
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Diazinon CAS:333-41-5 Mugadziri Mutengesi
Diazinon inowanikwa nenzira yemvura isina ruvara kana yakasviba.Inonyungudika zvishoma mumvura asi inonyungudika mupetroleum ether, doro, uye benzene.Diazinon inoshandiswa kudzora zvakasiyana-siyana zvekurima uye zvipembenene zvemumba.Izvi zvinosanganisira tupukanana muvhu, pamiti yekushongedza, michero, muriwo, uye zvirimwa uye zvipembenene zvemumba zvakaita senhunzi, nhata, nemapete.
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Avermectin CAS:71751-41-2 Mugadziri Mutengesi
Abamectin (Avermectin) inhengo yetsinga ine chepfu.Maitiro ayo anonangana neGABAA receptor yezvipembenene neuron synapse kana neuromuscular synapse, ichikanganisa kufambiswa kweruzivo rwemagumo etsinga, kureva kukurudzira magumo etsinga kuburitsa neurotransmitter inhibitor γ-aminobutyric acid (GA-BA), zvichikurudzira kuvhurwa kwakawanda kweiyo. GABA-gated chloride channel ine chloride channel-activating effect.
