(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate CAS:955406-14-1

(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate inoita basa rakakosha sechikamu chepakati mukugadzirwa kwemakemikari akaomarara, anoshanda mumuviri ane mukana wekushandiswa mumishonga. Hunhu hwayo hwechiral uye chimiro chayo chakasiyana zvinoiisa sechinhu chakakosha pakugadzirwa kwemakemikari e-enantiopure, ayo akakosha mukugadzirwa kwemishonga. Nekubatanidza ichi chivakwa mumamorekuru, vaongorori vanogona kutsvaga mishonga mitsva inotarisa nzvimbo dzekurapa dzakadai sezvirwere zvepakati petsinga, zvirwere zvinotapukira, kana oncology. Mukemikari yemishonga, iyi kemikari inogona kushanda senzvimbo yekutanga yekugadzira mishonga inogona kuvepo, ichishandisa stereochemistry yayo kugadzirisa mashandiro ebhayoloji uye pharmacokinetic properties. Boka retert-butyl rinopa chipingamupinyi chesteric uye rinopesvedzera kusangana kwekomikari nezvinangwa zvebhayoloji, zvichibatsira mukutsvaga kurapwa kutsva. Uyezve, munzvimbo dzedzidzo nedzemaindasitiri, vaongorori vanogona kushandisa iyi kemikari kugadzirira maraibhurari emhando dzakasiyana dzezvidzidzo zvehukama hwechimiro-basa, zvichiita kuti zvikwanise kuzivikanwa kwemakemikari emutobvu ane mhedzisiro yebhayoloji inodiwa. Basa rayo mukugadzirwa kwemakemikari rinowedzera kusvika pakugadzirwa kwemishonga inopindirana uye kugadzirwa kwenzira itsva dzekugadzira, zvichiratidza kushanda kwayo kwakakura muzvidzidzo zvesainzi. Kazhinji, (R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate inoita basa guru mukutsvaga kuwanikwa kwemishonga mitsva uye kugadzirwa kwemishonga isina kuenzana, ichipa chikuva chekugadzirwa kwemamorekuru akasiyana-siyana anoshanda nehupenyu uye mishonga inopindirana.