Rapamycin kubva kuStreptomyces hygroscopicus CAS:53123-88-9

Rapamycin chinhu chinogadzirwa kubva mubhakitiriya reStreptomyces hygroscopicus. Chine mabasa akasiyana-siyana ehupenyu uye chinozivikanwa zvikuru nemasimba aro ekudzora immune system uye ekudzivirira kenza.

Pakutanga yakawanikwa semushonga unodzivirira hutachiona, rapamycin yakawanikwa iine simba guru rekudzora immune system, zvichiita kuti ive yakakosha pakuisirwa nhengo dzemuviri kudzivirira kurambwa. Izvi zvinoita nekudzivisa kushanda uye kuwanda kwemasero eT, chinhu chakakosha pakudzivirira immune system.

Pamusoro pezvo, rapamycin yakaratidza mhedzisiro yakanaka mukurapa kenza dzakasiyana-siyana. Inoshanda nekudzivisa puroteni inonzi mTOR (chinangwa chemamalia che rapamycin), iyo inoita basa rakakosha mukukura nekupatsanurwa kwemasero. Nekuvharira mTOR, rapamycin inobatsira kudzora kukura kwemasero ekenza kusingadzoreki.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Kubatsira Kwekudzivirira Kupararira Kwemasero Emuviri: Rapamycin inodzivirira kushanda uye kuwanda kwemasero eT, ayo akakosha pakuita kwekudzivirira muviri. Izvi zvinodzvinyirira masero emuviri zvinoita kuti abatsire pakuisa nhengo dzemuviri kudzivirira kurambwa.

Kurwisa Gomarara: Rapamycin yaratidza kugona kwayo kurwisa gomarara. Inodzivirira puroteni inonzi mTOR, iyo inobatanidzwa mukukura nekupatsanurwa kwemasero. Nekutarisa mTOR, rapamycin inobatsira kudzora kukura kwakanyanya kwemasero egomarara. Yakadzidzwa nezvemhando dzakasiyana dzegomarara, kusanganisira kenza yemazamu, prostate, mapapu, uye renal cell carcinoma.

Kurapa Zvirwere Zvisingawanzoitiki: Rapamycin yakatenderwa kurapa zvimwe zvirwere zvisingawanzoitiki, zvakaita se lymphangioleiomyomatosis (LAM) uye tuberous sclerosis complex (TSC). Zvirwere izvi zvinosanganisira kukura kusingawanzoitiki kwemasero munhengo dzakasiyana-siyana, uye rapamycin inobatsira kudzora zviratidzo uye kufambira mberi kwechirwere.

Migumisiro yekudzivirira kuzvimba: Rapamycin yakaratidza simba rekudzivirira kuzvimba. Inogona kudzivirira mamwe masero ekudzivirira muviri nemapuroteni ekudzivirira kuzvimba, izvo zvinogona kubatsira muzvirwere zvine chekuita nekuzvimba kwenguva refu, zvakaita sezvirwere zve autoimmune.

Matambudziko Etsinga: Tsvagiridzo inoratidza kuti rapamycin inogona kurapa zvirwere zvinoderedza mashandiro etsinga zvakaita sechirwere cheAlzheimer nechirwere cheParkinson. Yakaratidza mhedzisiro yekudzivirira tsinga uye yekudzivirira kukwegura muzvidzidzo zvepamberi pekiriniki, asi tsvakiridzo yakawanda inodiwa.

Kurwisa Kukwegura uye Kurarama Kwenguva Refu: Rapamycin yave kuzivikanwa nekuda kwekugona kwayo kuwedzera hupenyu hwemunhu uye kukurudzira kukwegura kwakanaka. Yakadzidzwa muzvinhu zvipenyu zvakasiyana-siyana, uye mhedzisiro yakaratidza kuwedzera kwehupenyu hwemunhu uye kuvandudzwa kwenguva yehutano.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C51H79NO13
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	53123-88-9
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.