Spironolactone CAS:52-01-7 Mugadziri Mutengesi

Spironolactone (Aldactone) ikamu rakagadzirwa semineralocorticoid antagonist uye rinoshandiswa se diuretic uye antihypertensive agent.Zvisinei, pamazinga akakwirira spironolactone inosunga kune androgen receptor.Mumakiriniki maitiro ndeye androgen anopikisa asina simba anoshandiswa kurapa hirsutism muvakadzi nekuvhara testosterone inosunga kune androgen receptors mubvudzi follicles.Kushandiswa kwe spironolactone muvakadzi pakurapa hirsutism kana mhanza yevarume inogona kukonzera kukwirira kweserum potassium;mazinga aya anofanira kuongororwa mukati memwedzi we1 kutanga mishonga.Spironolactone (Aldactone) yakarongeka yakabatana nealdosterone uye inoshanda semakwikwi inhibitor kudzivirira kusungirirwa kwealdosterone kune yayo chaiyo cellular binding protein.