Clascoterone CAS:19608-29-8 Mugadziri Mutengesi Mufananidzo Wakaratidzwa

Clascoterone CAS:19608-29-8 Mugadziri weMugadziri

Clascoterone mushonga unodzivirira androgen receptor uri kugadzirwa sekirimu uye mushonga wepamusoro neCassiopea (kambani inosanganisa Cosmo Pharmaceuticals) yekurapa zvirwere zveganda zvinotsamira pa androgen, zvinosanganisira androgenetic alopecia uye acne vulgaris. Kunyangwe nzira chaiyo yekushanda kwe clascoterone pakurapa acne vulgaris isingazivikanwe, mushonga uyu unofungidzirwa kuti unokwikwidzana ne androgen dihydrotestosterone pakusunga kune androgen receptors mu sebaceous gland uye bvudzi follicles kuderedza zviratidzo zvinodiwa pakukura kwe acne.

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Kushandiswa uye Mhedzisiro

Clascoterone iri kugadzirwa sekirimu yemushonga weganda neCassiopea yezvirwere zveganda zvinoenderana ne androgen. Clascoterone (cortexolone 17α-propionate, CB-03-01) inyanzvi itsva ye androgen receptors. Inosunga kuma androgen receptors nehukama hwakakura. Nekukwikwidzana nema androgens kuti abatanidze kuma androgen receptors, clascoterone inoshanda nekudzivirira ma androgen receptor signalling cascades anokurudzira hutachiona hwemapundu, akadai sekuwedzera kwe sebaceous gland, kugadzirwa kwe sebum yakawandisa, uye nzira dzekuzvimba. Muna Nyamavhuvhu 2020, FDA yakabvumidza clascoterone yekurapa mapundu ekutanga mukirasi (acne vulgaris) muvarwere vechirume nevakadzi vane makore gumi nemaviri zvichikwira. Clascoterone iri kuferefetwawo senzira itsva yekurapa ma androgenetic alopecia.

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Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C24H34O5
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	19608-29-8
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.