TOPS CAS:40567-80-4 Mutengo wemugadziri

Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate, inozivikanwawo seMESNa, ine simba rayo uye mashandisirwo ayo mu biochemistry uye molecular biology. Inonyanya kushandiswa semushonga wekuderedza huwandu hwe thiol (-SH) mumapuroteni nema peptides.

MESna inoshanda semushonga une simba wekuderedza mapuroteni, inokwanisa kushandura ma disulfide bonds (-SS-) mumapuroteni kuita mapoka e sulfhydryl (-SH). Maitiro aya ekuderedza mapuroteni akakosha mukushandiswa kwakasiyana-siyana kwesainzi, kusanganisira kuongorora mapuroteni, kucheneswa, uye hunyanzvi hwemapuroteni.

Mamwe mashandisirwo chaiwo eMESna anosanganisira:

Kuchinja kweMapuroteni: MESNa inogona kushandiswa kuderedza mapuroteni nekutyora mabhondi e disulfide, nokudaro ichivhura chimiro chepuroteni uye ichibatsira kuongororwa kwakawanda kana kucheneswa kwepuroteni.

Kuderedza Kuunganidzwa kweMapuroteni: MESNa inogona kudzivirira kuunganidzwa kweprotein nekuderedza disulfide bonds, zvichiita kuti mapuroteni agare zvakanaka uye anyungudike mumushonga.

Kunyora Mapuroteni: MESNa inogona kushandiswa kuisa mavara kana shanduko pane zvakasara zve cysteine ​​mumapuroteni nekutyora ma bond e disulfide uye kuburitsa pachena mapoka e sulfhydryl (-SH).

Kudzokororwa kweMapuroteni: MESna inoshandiswa kubatsira kudzokororwa kweprotein mushure mekucheneswa kwemasero nekuderedza disulfide bonds uye kubatsira mukuumbwa kwemapuroteni nemazvo.