Trt-Cys(Trt)-OH ·DEA CAS:27486-88-0

Trt-Cys(Trt)-OH·DEA inoita basa rakakosha mukugadzirwa kwepeptide, kunyanya mukugadzirira mapeptide ane cysteine ​​ayo akakosha mukudzidza kwekudyidzana kwemapuroteni nemapuroteni, hukama hwe enzyme-substrate, uye hukama hwechimiro-basa. Boka re trityl rinoshanda seboka rinodzivirira mashandiro e thiol e cysteine, zvichigonesa kusarudzwa kwekudzivirira panguva yekuungana kwe peptide. Uyezve, iyi compound inoshandiswa mukugadzirwa kwe peptide yakasimba, nzira yakakosha mu peptide chemistry uye kuedza kuwana mishonga, zvichibvumira kugadzirwa kwema peptide matsva uye peptidomimetics ane mukana wekushandiswa kwekurapa. Uyezve, Trt-Cys(Trt)-OH·DEA inobatsira mukusimudzira kunzwisisa kwedu hukama hwe peptide structure-function uye inoshanda sechinhu chakakosha mukutsvaga mativi akasiyana esainzi ye peptide. Kushanda kwayo kunosvika pakuferefeta mu bioconjugation uye chemistry biology, zvichiita kuti ma peptides asanganiswe nemamwe mamorekuru kuti apihwe kana kuongororwa. Kazhinji, inomira sechishandiso chakakosha, ichigonesa vaongorori kuti vaongorore kuomarara kwemakemikari epeptide uye zvazvinoreva pakutsvagisa kwezvekurapa, kugadzira mishonga, uye nzira dzekurapa dzinogona kushandiswa. Nekushandiswa kwayo kwakasiyana-siyana mukutsvagisa kwepeptide, reagent iyi inokosha zvikuru mukusimudzira ruzivo rwesainzi uye kubatsira mukuvandudzwa kwemishonga yekurapa yakavakirwa papeptide.