Trt-Gly-OH CAS:5893-05-0

Bz-His-OMe inoita basa rakakosha mukugadzirwa kwepeptide, ichiva chinhu chikuru chekuvaka mapeptide ane hunhu hwakananga hwechimiro uye mashandiro. Boka rinodzivirira benzyl rinoona kuti histidine residue inoramba isina kuchinjwa panguva yekugadzira peptide, zvichibvumira kuungana kwepeptide kwakarurama uye kwakadzorwa. Pamusoro pezvo, kuvapo kweboka remethyl ester kunokanganisa reactivity yemakemikari uye kudyidzana kwe hydrophobic kwepeptide, zvichiita kuti ive yakakosha pakugadzira mapeptide ane membrane permeability yakawedzerwa kana kugona kwakanangana. Mukugadzirwa kwemishonga, iyi compound inogona kushandiswa kugadzira mishonga yakavakirwa papeptide ine kugadzikana kuri nani uye bioavailability yakawedzerwa, zvingangotungamira mukuwedzera kushanda kwekurapa. Kuwedzera kune basa rayo mukugadzirwa kwepeptide, Bz-His-OMe inowana kushandiswa muproteomics uye biochemical research, uko inogona kushandiswa kudzidza kudyidzana kwemaprotein nemaprotein, kuongorora enzyme activity, uye kuongorora pH-dependent conformational changes mumaprotein. Maumbirwo ayo akagadzirwa anobvumira vaongorori kuongorora kuomarara kwema cellular processes uye masystems ezvirwere, zvichibatsira mukufambira mberi mukunzwisisa hutano uye pathology. Kushanda nesimba kwemushonga uyu mumamiriro akasiyana-siyana ekuyedza kunoita kuti uve chinhu chakakosha pakubvisa kuoma kwemasisitimu ezvipenyu uye kugadzira nzira dzakanangana nezvirwere zvakasiyana-siyana. Mukupfupisa, Bz-His-OMe inomiririra chishandiso chakakosha kune vaongorori mukugadzira mapeptide, kugadzira mishonga, uye zvidzidzo zvebiochemical, ichipa kugona kugadzirisa mapeptide ane hunhu hwakasiyana uye kuburitsa mashandiro ezvipenyu, nokudaro ichibatsira mukufambira mberi mukurapa nebiotechnology.