VALINOMYCIN CAS:2001-95-8 Mutengo wemugadziri

Valinomycin mushonga we cyclic peptide antibiotic unogadzirwa zvakanyanya nemarudzi akasiyana eStreptomyces bacteria. Unoumbwa ne cycle ye alternating D- neL-amino acids, ine central cyclic depsipeptide motif. Valinomycin inozivikanwa ne high affinity yayo ye monovalent cations, kunyanya potassium ions (K+).

Nekuda kwekugona kwayo kusunga nekutakura maion epotassium kuburikidza ne membranes dzezvipenyu, valinomycin yakawana mashandisirwo akasiyana-siyana mukutsvaga kwesainzi uye biotechnology. Inoshandiswa zvakanyanya se ionophore muma electrodes anosarudza maion ekuyera huwandu hwe potassium mu sampuli dzezvipenyu. Kugona kweValinomycin kutakura maion epotassium nenzira yakasarudzika kunoitawo kuti ibatsire muzvidzidzo zvekutakura maion uye kugona kwemembrane mumasero.

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Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Valinomycin inonyanya kushanda se ionophore, zvichireva kuti inobatsira kutakurwa kwema ions chaiwo kuburikidza nemasero. Mhedzisiro yayo inonyanya kuzivikanwa ndeyekubatana kwayo kwakasimba nema potassium ions (K+). Valinomycin inoumba complex ine K+ ions, zvichiita kuti ive yakasarudzika zvakanyanya pakuitakura.

Imwe yenzira huru yekushandisa valinomycin ndeyekushandisa ionophore muma electrode anosarudza ion pakuyera huwandu hwe potassium muzviyero zve biological. Ma electrode aya anoshandisa kugona kwevalinomycin kusunga nekutakura ma K+ ions nenzira yakasarudzika, zvichiita kuti kuyerwa kwema potassium ion kwakarurama uye kwakaringana.

Kugona kweValinomycin kutakura maion epotassium kunoitawo kuti ive yakakosha muongororo ine chekuita nekutakura maion uye kugona kwemembrane mumasero. Inoshandiswa kudzidza basa remaion channels, kugona kwemembrane, uye maion gradients mumaitiro akasiyana-siyana ehupenyu.

Uyezve, valinomycin yakaongororwa kuti inogona kushandiswa sei pakurapa. Yakaratidza mhedzisiro yakanaka semushonga wekurwisa kenza mune mamwe marudzi ekenza. Valinomycin inokonzera kufa kwemasero mumasero ekenza nekukanganisa kugona kwawo kwemasero emumitochondrial.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C54H90N6O18
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	2001-95-8
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.