Vhitamini B13 (Orotic Acid) CAS: 65-86-1 Mugadziri Mutengesi

Orotic acid (inozivikanwawo se pyrimidinecarboxylic acid) iheterocyclic acid; inozivikanwawo se. Kare yaifungidzirwa kuti iri chikamu chevhitamini B uye yainzi vhitamini B13, asi ikozvino yava kuzivikanwa kuti haisi vhitamini. Inozivikanwa senzira yekutanga mukugadzirwa kwepyrimidines; mumhuka dzinoyamwisa inoburitswa kubva mumitochondrial dihydroorotate dehydrogenase (DHODH) kuti ishandurwe kuita UMP ne cytoplasmic UMP synthase enzyme. OA chikamu chakajairika chekudya, inowanikwa mumukaka nezvigadzirwa zvemukaka, uye inoshandurwa kuita uridine kuti ishandiswe munzira ye pyrimidine salvage kunyanya muchiropa, itsvo uye erythrocytes.

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Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

Orotic acid imhando yepakati mu de novo pyrimidine biosynthesis inogona kushandiswa kudzidza specificity uye kinetics ye orotate phosphoribosyltransferase (OPRT) iyo inokonzeresa reversible phosphoribosyl transfer kubva ku 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) kuenda ku orotic acid (OA), zvichigadzira pyrophosphate uye orotidine 5?-monophosphate (OMP). Inoshandiswa senzira yekutanga yekugadzirwa kwe uridine 5?-monophosphate (UMP) nehutachiona hwakadai seCorynebacterium ammoniagenes (ATCC 6872) kana Saccharomyces cerevisiae. Inogona kushandiswa kudzidza nzira yeAMPK/SREBP-1 dependent cell signaling pathway uye transcription regulation mechanisms inokonzera hepatic lipogenesis.

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Mamwe Mashoko:

Kuumbwa	C5H4N2O4
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	65-86-1
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.