Z-MeVal-OH CAS:42417-65-2

Chigadzirwa ichi chinoshandiswa zvakanyanya nevaongorori nemakambani emishonga pakugadzira mapeptide ane N-methylvaline residues. N-methylvaline inozivikanwa nekukwanisa kwayo kuwedzera kugadzikana kwechimiro uye kupinda kwe membrane kwema peptides, zvichiita kuti ive chinhu chakakosha mukugadzirwa kwemishonga nekurapa zvinobva mu peptide. Z-MeVal-OH yakachena kwazvo uye inoenderana nemamwe ma reagents, zvichiita kuti ive sarudzo yakavimbika yemapurojekiti ekugadzira peptide. Z-MeVal-OH chishandiso chinoshandiswa nevaongorori muminda ye biochemistry, pharmacology, uye kuwanikwa kwemishonga. Kugadzikana kwayo, kuchena kwayo, uye kuenderana kwayo kunoita kuti ive chinhu chakakosha mukugadzirwa kwema peptide ane N-methylvaline, ayo anogona kushandiswa mukugadzirwa kwemishonga, kutsvagisa kwezvipenyu, uye kupindira kwekurapa. Nekubatanidza Z-MeVal-OH muzvikamu zve peptide, vaongorori vanogona kugadzira makemikari matsva ane hunhu hwakanaka hwe bioactivity uye pharmacokinetic, zvichisimudzira munda wekuwana mishonga inobva mu peptide.