β-Nicotinamide Mononucleotide CAS:1094-61-7

Nicotinamide mononucleotide (NMN), chigadzirwa cheNAMPT reaction uye chinhu chakakosha cheNAD+ intermediate, inovandudza kusashivirira kweglucose nekudzorera mazinga eNAD+ mumakonzo eT2D anokonzerwa neHFD. NMN inowedzerawo kunzwa kwe insulin muhepatic uye inodzorera kuratidzwa kwemajini ane chekuita nekushushikana kwe oxidative, mhinduro yekuzvimba, uye circadian rhythm, zvishoma kuburikidza neSIRT1 activation. NMN inoshandiswa pakudzidza ma binding motifs mukati meRNA aptamers uye ribozyme activation processes inosanganisira β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Odha kana Kumbira Mutengo

Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Kushandiswa uye Mhedzisiro

β-Nicotinamide mononucleotide (NMN) inoshandiswa kudzidza ma "binding motifs" mukati meRNA aptamers uye maitiro e "ribozyme activation" anosanganisira β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. NMN i "nucleotide" inobva ku "ribose" uye "nicotinamide". Niacinamide (nicotinamide,) inobva ku "vitamin B3", inozivikanwawo se "niacin". Senzira yekurapa nemakemikari yeNAD+, inogona kubatsira mukudzivirira pellagra.
β-Nicotinamide mononucleotide inhengo iri pakati pekugadzirwa kwe nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) inokonzeresa kuunganidzwa kwe nicotinamide ne 5-phosphoribosyl-1-pyrophosphate kuti igadzire β-NMN, iyo inozoshandurwa kuita NAD+ ne β-NMN adenyltransferase. Pa 50-100 μM, β-NMN yakashandiswa kuwedzera kugadzirwa kwe NAD uye kuburitswa kwe insulin inokonzereswa ne glucose muNampt+/- mouse model yechirwere che metabolic, zvichiratidza basa reNampt mukushanda kwe β cell.

Muenzaniso weChigadzirwa

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C11H15N2O8P
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	1094-61-7
Kurongedza	25KG
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.