Acetylthiocholine iodide CAS:1866-15-5

Acetylthiocholine iodide ikemikari inoshandiswa zvakanyanya mukuyedza ma enzymes kuti ione mashandiro e enzyme acetylcholinesterase (AChE). AChE i enzyme inonyungudutsa neurotransmitter acetylcholine, danho rakakosha mukugumisa kutumira kwechiratidzo pakati pemasero etsinga.

Kana acetylthiocholine iodide ikashandiswa neAChE, boka reacetyl rinobviswa, zvichikonzera kuumbwa kwe thiocholine ne acetate ions. Thiocholine inobva yaita reactive ne reagent isina ruvara inonzi DTNB (5,5′-dithiobis(2-nitrobenzoic acid)) kuti igadzire compound yeruvara rweyero inonzi 5-thio-2-nitrobenzoate, iyo inogona kuyerwa ne spectrophotometric. Mwero wekukura kweruvara unoenderana zvakananga nebasa reAChE mumuenzaniso.

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Kushandiswa uye Mhedzisiro

Kuyerwa kwebasa reacetylcholinesterase (AChE): Acetylthiocholine iodide inowanzo shandiswa sechikamu chemuyedzo weenzyme kuyera basa reAChE. AChE ienzyme inonyungudutsa acetylcholine, uye nekuyera basa rayo, vaongorori vanogona kuongorora mashandiro echolinergic uye mhedzisiro yemishonga, chepfu, kana zvirwere paAChE.

Chishandiso chekuongorora zvirwere zve neurodegenerative: Kusashanda zvakanaka kweAChE kunoonekwa muzvirwere zvakasiyana-siyana zve neurodegenerative, kusanganisira chirwere cheAlzheimer. Kuyerwa kwebasa reAChE uchishandisa acetylthiocholine iodide kunogona kubatsira mukuongorora nekutarisa zvirwere zvakadaro.

Zvidzidzo zveToxicology: Acetylthiocholine iodide inoshandiswawo muzvidzidzo zveToxicology kuongorora mhedzisiro yemakemikari kana chepfu pabasa reAChE. Mamwe makemikari, akadai se organophosphate uye carbamate insecticide, anogona kudzivirira basa reAChE, zvichikonzera migumisiro ine chepfu. Acetylthiocholine iodide inogona kupa ruzivo nezve chepfu uye mashandiro ekushanda kwemakemikari aya.

Kuongororwa kwemishonga inodzivirira AChE: Acetylthiocholine iodide inoshandiswa mukutsvaga nekugadzira mishonga yekuongorora nekuona mishonga inogona kudzivirira AChE. Mishonga inodzivirira AChE inogona kubatsira mukurapa zvirwere zvakasiyana-siyana, kusanganisira chirwere cheAlzheimer's.

Kugadzirwa kwema biosensors: Acetylthiocholine iodide, pamwe chete neAChE, inoshandiswa mukugadzira biosensors yekuona acetylcholine. Aya biosensors anoshandiswa munzvimbo dzakadai sekutarisa nharaunda uye kuongororwa kwekiriniki.

Kurongedza Chigadzirwa:

Mamwe Mashoko:

Kuumbwa	C7H16INOS
Kuyedza	99%
Chitarisiko	Upfu chena
Nhamba yeCAS	1866-15-5
Kurongedza	Diki uye rakakura
Hupenyu hweSherufu	makore maviri
Kuchengetera	Chengeta munzvimbo inotonhorera uye yakaoma
Chitupa	ISO.