Boc-Ile-ONp CAS:16948-38-2

Boc-Ile-ONp inoshandiswa zvakanyanya mumaitiro ekugadzira mapuroteni nekuchinja mapeptide. Mukugadzira mapeptide, zvinoita kuti isoleucine residues ikwanise kudzorwa mu peptide sequence, zvichigonesa kubatana kwemapoka akasiyana-siyana anoshanda, ma label, kana mamorekuru ekushandisa zvakasiyana-siyana. Kugadziriswa uku kunobvumira kugadzirwa kwemapeptide akawanda ane hunhu hwakagadzirirwa, senge kugadzikana kwakawedzerwa, kutsanangurwa kwechinangwa, kana kugona kwekufungidzira. Mukutsvaga mapuroteni, Boc-Ile-ONp inogonesa kunyora mapuroteni nemapeptide zvakananga, zvichibatsira mukuongorora chimiro, zvidzidzo zvekudyidzana, uye kuyedza kwakavakirwa pahuwandu hwema spectrometry. Kubatanidzwa kweBoc-Ile-ONp kune isoleucine residues kunogonesa kutsanangurwa kwakarurama uye kuongororwa kwebasa remapuroteni nemapeptide, zvichitsigira kufambira mberi mukunzwisisa masisitimu ehupenyu uye nzira dzezvirwere. Uyezve, mukugadzirwa kwemishonga, Boc-Ile-ONp inoita basa rakakosha mukubatanidza mishonga yekurapa kumapeptide kana mapuroteni, kugadzira masisitimu ekupa mishonga akananga, ma antibody-drug conjugates, kana ma vaccine constructs ane pharmacokinetic profiles yakagadziridzwa uye kudzikira kwemhedzisiro isiriyo. Kazhinji, kuvimbika uye kushanduka-shanduka kweBoc-Ile-ONp mukugadzirisa peptide uye bioconjugation zvinoita kuti ive chishandiso chakakosha chekufambira mberi mukutsvaga mishonga, makemikari ebhayoloji, uye proteomics, zvichipa mikana yakasiyana-siyana yekugadzira mashandisirwo matsva ekurapa.