Boc-MeIle-OH CAS:52498-32-5

Boc-MeIle-OH inoshandiswa zvakanyanya mukugadzirwa kwepeptide yakasimba kugadzira mapeptide akagadzirwa nemaoko ane maitiro akasiyana uye mashandiro. Senzira yakachengetedzwa yeN-methyl-isoleucine, inogonesa kuiswa kwakadzorwa kweN-methyl-isoleucine residues mu peptide chain iri kukura, ichidzivirira kusawirirana kusingadiwe uye ichibvumira kugadzirwa kwepeptide dzakaoma dzine hunhu hwakagadzirirwa. Mu bioconjugation uye chemistry biology, Boc-MeIle-OH inoshanda sechivako chinoshanda zvakasiyana-siyana chekugadzira mapeptide anoshanda, ma probes ane mazita, uye peptide-based therapeutics. Kushandiswa kwayo kunogonesa kugadziriswa kwakanyatsojeka kwepeptides nemapuroteni, zvichibatsira kukura kwemamorekuru anoshanda akawanda ane kugadzikana kwakawedzerwa, chinangwa chaicho, kana kugona kwekufungidzira kwezvishandiso zvakasiyana-siyana zve biomedical. Uyezve, mukuwana mishonga nekuvandudza kurapa, Boc-MeIle-OH inoshandiswa kugadzira ma peptide conjugates uye ma peptide akagadziriswa ane pharmacokinetic profiles yakagadziridzwa uye mabasa e biological. Kugadziriswa uku kunogona kuwedzera kushanda, kusarudza, uye kuendeswa kwemishonga yakavakirwa papeptide, zvichibatsira mukufambira mberi mukurapa kwakaringana uye kurapwa kwakanangana. Kazhinji, kuvimbika uye kushanduka-shanduka kweBoc-MeIle-OH mukugadzirwa kwepeptide uye bioconjugation kunoita kuti ive chishandiso chakakosha chekufambira mberi mukutsvaga mishonga, makemikari ebhayoloji, uye proteomics, zvichipa mikana yakasiyana-siyana yekugadzira mashandisirwo matsva ekurapa.